摘要
目的:探讨C-反应蛋白(CRP)在慢性阻塞性肺疾病急性加重期(AECOPD)并高血糖患者治疗前后的变化及其临床意义。方法:选取32例AECOPD患者及30例AECOPD并高血糖患者,另取门诊稳定期慢性阻塞性肺疾病(COPD)患者30例作为对照组。分别检测AECOPD患者(AECOPD组)、AECOPD并高血糖患者(高血糖组)治疗前后及门诊稳定期COPD患者(稳定组)血清CRP水平。结果:CRP在AECOPD组治疗前与高血糖组治疗前比较有显著性差异(P<0.05),且2组均高于稳定组水平,两两比较有统计学意义(P<0.05)。CRP在AECOPD组治疗后与高血糖组治疗后比较有显著性差异(P<0.05)。前者与稳定组比较无显著性差异(P>0.05),后者与稳定组比较有统计学意义(P<0.05)。CRP在AECOPD组及高血糖组治疗前后比较有显著性差异(P<0.05)。结论:CRP水平增高与COPD炎症反应及高血糖的炎性作用重叠相关。
Objective：To evaluate the changes of C-reactive protein before and after treatment of acute exacerbation of chronic obstructive pulmonary disease with hyperglycemia,to analyze its clinical significance.Methods：Selected 32 patients with AECOPD and 30 patients with AECOPD with hyperglycemia,selected other 30 cases outpatients with stable COPD as control group.Detected the serum CRP levels of patients with AECOPD（AECOPD group） and patients with AECOPD with hyperglycemia（the hyperglycemia group） before and after treatment,detected the serum CRP levels of outpatients with stable COPD（the steady group）.Results：The serum concentrations of CRP in the AECOPD group and in the hyperglycemia group before treatment were difference,there was statistically significant（P0.05）.And the two groups were higher than the steady group,the difference was statistically significant（P0.05）.The serum concentrations of CRP in the AECOPD group and in the hyperglycemia group patients after treatment were the difference,there was statistically significant（P0.05）.The difference between the former and the steady group was a lack of statistically significant（P0.05）,the difference between the latter and the steady group was statistically significant（P0.05）.CRP in the AECOPD group and in the hyperglycemia group was significant difference between before and after treatment（P0.05）.Conclusion：The serum concentrations of CRP with COPD inflammation and inflammatory effects of hyperglycemia are correlated overlap.
出处
《现代临床医学》
2011年第1期33-35,共3页
Journal of Modern Clinical Medicine
