摘要
目的:探寻脑梗死后抑郁症的较佳疗法。方法:将80例脑梗死后抑郁症患者随机分为两组。针刺组(40例)采用头、体针相结合的治疗方法。西药组(40例))口服盐酸氟西汀每天20mg,两组均治疗6周,分别对两组治疗前及治疗第6周末进行汉密尔顿抑郁量表(HAMD)评分,采用副反应量表(TESS)评定不良反应。结果:针刺组总有效率为95.0%,西药组总有效率为90.0%,两组比较差异无统计学意义(P>0.05)。HAMD评分两组治疗6周后与治疗前比较差异均有统计学意义(均P<0.01);两组间治疗后比较差异无统计学意义(P>0.05)。治疗结束后两组间TESS评分比较差异有统计学意义(P<0.01),针刺组基本无不良反应,西药组表现为恶心、厌食、腹泻等。结论:头、体针相结合治疗脑梗死后抑郁症与服用盐酸氟西汀疗效相当,且安全、无不良反应。
Objective：To search for an effective therapy for post cerebral infarction depression. Methods：80 cases were randomly divided into two groups. The acupuncture group （40cases） was treated with head - acupuncture and body - acupuncture. The western medicine group （40 cases） was treated with oral administration of Fluoxetine Hydrochlo- ride at the dosage of 20 mg every day. These treatments lasted for 6 weeks in both groups. The depression severities were assessed with Hamilton Depression Scale （HAMD） before treatment and at the 6th week of the treatment and adverse reac- tions were appraised respectively with Treatment Emergent Symptom Scale （TESS）. Results：The total effective rate was 95.0% in the acupuncture group and 90.0% in the western medicine group with no significant difference between the two groups （ P 〉 O. 05 ）. After treatment, the HAMD score had very significant changes in the two groups as compared with those before treatment （both P 〈 0.01 ）, but there was no significant difference between the two groups （P 〉 0.05）. After treatment, there was a significant difference between two groups in TESS score （P 〈0.01 ）. There was almost no adverse reaction in the acupuncture group, while the main clinical manifestations in the western medicine group were nausea, anorexia, diarrhea, etc. Conclusion：Head-acupuncture combined with body-acupuncture can significantly improve symptoms of post cerebral infarction depression patients with a similar therapeutic effect to oral administration of Fluoxetine Hydro - chloride and it is a safe method for post cerebral infarction depression without adverse reactions.
出处
《中华中医药学刊》
CAS
2011年第2期409-411,共3页
Chinese Archives of Traditional Chinese Medicine
关键词
头针
体针
脑梗死后抑郁
Head- acupuncture
body-acupuncture
post cerebral infarction depression
