摘要
目的观察舒芬太尼、芬太尼全麻诱导期老年患者气管插管时心血管反应,为临床上选择全麻诱导期患者气管插管用药提供临床依据。方法将100例择期全麻手术患者随机分为芬太尼组(F组)、舒芬太尼组(SF组),每组各50例。记录诱导前(T0)、给予芬太尼或舒芬太尼后即刻(T1)、插管前(T2)、插管即刻(T3)及插管后2、4、6、8min(T4-T7)时的收缩压(SBP)、舒张压(DBP)、平均动脉压(MAP)及心率(HR)。结果 SF组插管前后SBP、DBP、MAP无明显变化(P>0.05),且各时间点变化无统计学差异(P>0.05);T3、T4HR增快与T2比较有统计学差异(P<0.05)。F组T3、T4、T5、T6SBP、DBP、MAP高于T2(P<0.05),且T3、T4、T5两两比较有差异(P<0.05);HR于T7恢复至T2水平。结论舒芬太尼在全身麻醉诱导中应用,可使插管前后的血流动力学更加平稳。
Objective To observe the cardiovascular effects of sulfentanyl and fentanyl on case of general anesthesia derivative phase when trachea cannula and to provid clinic evidence of choosing the drugsfor general anesthesia derivative phase when trachea cannula.Methods 100 cases received the selective operation with general anesthesia were divided into the SF group and F group with 50 cases in each group. The SBP,DBP,MAP and HR were recorded before induction of anesthesia（T0）, after injection of fentanyl or sulfentanyl（T1）, before trachea cannula（T2）,the monment of trachea cannula（T3）and in 2、4、6、8 minutes after cannala（T4-T7）.Results The SBP,DBP,MAP in SF group after cannula were same to those before cannula and the values were no difference at every time（P0.05）;HR increased at T3、T4 compared with T2（P0.05）. The SBP,DBP,MAP atT3、T4、T5、T6 in F group were higher than T2（P0.05）.Conclusion Application of sufentanil causes were more stable hemodynamics during general anesthesia derivative phase when trachea cannula.
出处
《中国实用医药》
2011年第2期52-53,共2页
China Practical Medicine
关键词
舒芬太尼
芬太尼
气管插管
血压
Sulfentanyl
Fentanyl
Trachea cannula
Blood pressure
