摘要
目的:探讨运动实验中P波时限(P-wave duration,PWD)变化对心肌缺血的诊断价值。方法:收集87例已确诊的冠心病患者及35例正常对照者,均行运动平板试验,测量并计算运动前及运动后第1分钟平均PWD,计算PWD变化值(△PWD),应用ROC曲线分析法评价△PWD对心肌缺血的诊断价值。结果:冠心病患者组与对照组运动前平均PWD分别为(92.89±10.21)ms,(90.76±15.05)ms(P>0.05),运动后分别为(114.47±10.25)ms和(106.64±16.44)ms(P<0.01),冠心病患者组与对照组△PWD比较,有统计学差异(P<0.01)。ROC曲线分析诊断截点定为19.5ms时Youden指数最大,此时灵敏度为74.5%,特异度为84.8%。结论:测量平板运动试验中PWD改变可以作为诊断心肌缺血的指标之一,并提高运动试验对心肌缺血的诊断价值。
Objective：The aim of this study was to investigate the diagnosis value of the differences in p-wave duration （PWD） due to exercise-induced myocardial ischemia.Method：The CAD （Coronary Artery Disease） group consisted of 87 patients with coronary artery disease and a control group of 35 subjects,treadmill testing was performed in all of them.Signal-averaged P waves duration was measured before exercise and at 1 minutes into recovery,the change in p-wave duration （PWD） was calculated.Ananysis the the diagnosis value of the differences in p-wave duration （PWD） by ROC curve.Result：The mean PWD before exercise in the CAD group and control group was 92.89±10.21ms and 90.76±15.05 ms （P0.05）,at the first minute of recovery it was 114.47±10.25 ms and 106.64±16.44ms respectively （P0.01）.△PWD were found to be statistically significant （P0.01） in the CAD group when compared with control group.Cutoff value of △PWD was 19.5 ms set up by ROC curve,the sensitivity and specificity of △PWD was 74.5% and 84.8%.Conclusion：The increase in P-wave duration was used as an additional parameter to detecting exercise-induced myocardial ischemia,increased the value of treadmill testing.
出处
《临床心血管病杂志》
CAS
CSCD
北大核心
2010年第12期914-916,共3页
Journal of Clinical Cardiology
关键词
冠心病
运动实验
P波时限
coronary disease
treadmill testing
P-wave duration
