摘要
目的：研究影响甲状腺乳头状微小癌（PTMC）术后复发的相关临床病理学因素。方法：回顾性分析124例PTMC患者的临床资料,采用单因素及多因素分析,探讨PTMC相关临床病理因素与术后复发的相关性。结果：平均随访57（18~120）个月,复发率为10.5%（13/124）,单因素分析显示肿瘤直径≥5 mm（P=0.013）、颈部淋巴结转移（P=0.001）、多发癌灶（P=0.007）及甲状腺包膜侵犯（P=0.000）与PTMC复发显著相关;多因素分析显示颈部淋巴结转移（P=0.001）、多发癌灶（P=0.007）及甲状腺膜包膜侵犯（P=0.000）与PTMC复发显著相关。结论：PTMC总体预后良好,但仍有较高的复发率,且复发与某些临床病理学因素显著相关,在决定手术方式时应充分考虑这些因素。
Objective： To evaluate the clinical and pathological factors affecting recurrence in Papillary thyroid microcarcinoma（PTMC）.Methods： One hundred and twenty-four patients diagnosed as PTMC and surgically treated from January 1997 to December 2006,and clinical records were evaluated retrospectively by univariate and multivariate analyses.Results： Incidence of recurrent disease was 10.5% after 57 months mean follow-up（range 18～120）.Univariate analysis detected that tumor≥5 mm in size（P=0.013）,metastases in neck lymph nodes（P=0.001）,presence of multifocal（P=0.007）,and presence of capsular invasion（P=0.000）,were related to recurrence By multivariate analysis,presence of metastases in neck lymph nodes（P=0.034）,multifocal（P=0.013）,and capsular invasion（P=0.004） were significantly related to tumor recurrence.Conclusion： Patients with PTMC have a favorable prognosis.Some clinical and pathological factors may correlate with recurrence of PTMC,appropriate treatment may be justified depending on the presence or absence of these risk factors.
出处
《中国现代普通外科进展》
CAS
2010年第12期970-973,共4页
Chinese Journal of Current Advances in General Surgery
关键词
甲状腺肿瘤
癌
乳头状
微小癌
复发
Thyroid neoplasms·Carcinome
papillary·Microcarcinoma·Recurrence
