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厄贝沙坦治疗慢性充血性心力衰竭的临床观察 被引量:4

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摘要 目的 观察在常规治疗慢性充血性心力衰竭(CHF)患者基础上加用厄贝沙坦的临床疗效。方法68例患者随机分成2组各34例,对照组给予强心、利尿、扩血管等常规治疗;治疗组在常规治疗基础上加用厄贝沙坦150mg/d,治疗90d,观察治疗前后心功能、6min步行实验距离及超声心动图左心室射血分数,左心室短轴缩短分数的变化。结果治疗组与对照组总有效率分别为88.24%(30/34)、67.65%(23/34),2组差异有统计学意义(P〈0.05)。左室射血分数治疗组治疗前、后分别为(42.4±2.6)%、(52.6±6.5)%,对照组治疗前、后分别为(41.2±5.4)%、(44.1±1.6)%;左心室短轴缩短分数治疗组治疗前、后分别为(17.0±4.2)%、(23.6±5.6)%,对照组治疗前、后分别为(16.8±3.2)%、(19.8±6.9)%;2组两项指标治疗后较治疗前均增加(P均〈0.05),且治疗组治疗后优于对照组(P均〈O.05)。结论厄贝沙坦治疗CHF临床疗效良好,且药物不良反应少,患者依从性好,是治疗CHF的有效药物。
出处 《中国综合临床》 2011年第2期142-143,共2页 Clinical Medicine of China
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