摘要
目的 探讨肺结核患者下呼吸道致病菌种分布特点、细菌耐药情况及并发肺感染时临床特征。方法 选１５６ 例痰普通菌或真菌培养发现致病菌株的肺结核患者，确定菌种后进行抗菌药物体外药敏检测。结果 １５６ 例患者痰细菌培养发现致病菌株２３９ 例次。其中革兰氏阴性杆菌２１０ 株（８７９ ％ ） ，真菌２１ 株（８８ ％ ） ，革兰氏阳性球菌８ 株（３３ ％ ） 。药物敏感检测环丙沙星敏感菌株最高为６０６ ％ ，利福平最低为４１ ％ 。结论 肺结核患者呼吸道致病菌种以革兰氏阴性杆菌居多，可能与患者免疫功能低下、滥用抗生素及抗结核药物有关。
Objective To investigate the characteristics of the distribution and drug resistant of pathogenicbacteria in lower respiratory tract of pulmonary tuberculosis cases ,and analyze the clinical manifestation w hen co m plicated with pneu monia . Methods 156 cases with pulmonary tuberculosis were taken for strain identification and sensi tivity test to antibiotic in vitro afterthe result positive of bacteria and fungus culture . Results All of 239 cases for pathogenicbacterialstrains were found in sputums bacterial culture of 156 patients. There were 210 strains of gram negative bacilli(87 9 % ) ;fungus were 21(8 8 % ) ;gram positive cocci were 8(3 3 % ) . The detection of drug sensitive test suggested thatciprofloxacin had the highest susceptibility ,rates was 60 6 % ,and rifampicin had thelowestsusceptibility ,only 4 1 % . Conclu sion The primary pathogenic bacteria were gram negative bacilliin lower respiratory tract of pulmonary tuberculosis patients . This may be related toim munodeficiency ,abuse antibiotic and treated with antituberculosis drugs .
出处
《中国防痨杂志》
CAS
1999年第3期144-146,共3页
Chinese Journal of Antituberculosis
关键词
肺结核
呼吸道
致病菌
菌种鉴定
临床分析
Tuberculosis ,pulm onary Respiratory tract Pathogenic bacteria
