摘要
进行性核上性麻痹(PSP)为进行性tau蛋白异常聚集所导致的神经系统变性疾病,临床特征性表现为姿势不稳、核上性眼球运动障碍、颈部肌张力障碍、构音障碍、假性延髓麻痹及痴呆等。1904年由Posev首先发现并描述其临床表现,1964年,Steele等将此病列为独立的神经系统疾病。
出处
《中国现代神经疾病杂志》
CAS
2011年第1期22-26,共5页
Chinese Journal of Contemporary Neurology and Neurosurgery
参考文献44
-
1Steele JC,Richardson JC,Olszewski J.Progressive supranuclear palsy:a heterogeneous degeneration involving the brain stem,basal gemglia and cerebellum with vertical gaze and pseudobulbar palsy,nuchal dystonia and dementia.ArchNeurol,1964,10:333-359.
-
2Litvan I.Progressive supranuclear palsy//Litvan I.Atypical parkinsonian disorders:clinical and research aspects.New Jersey:Humans Press,2005:287-308.
-
3Scharg A,Ben-Shlomo Y,Quinn NP.Prevalence of progressive supranuclear palsy and multiple system atrophy:a crosssectional study.Lancet,1999,354:1771-1775.
-
4Flament S,Delacourte A,Verny M.Abnormal Tau proteins in progressive supranuclear palsy:similarities and differences with the neurofibrillary degeneration of the Alzheimer type.Acta Neuropathol,1991,81:591-596.
-
5Ksiezak-Reding H,Morgan K,Mattiace LA,et al.Vltrastructure and biochemical composition of paried helical filaments in cortixcbasal degeneration.Am J Pathol,1994,145:1496-1508.
-
6Borroni B,Goldwarm S,Cerini C,et al.Familial aggregation in Progressive Supranuclear Palsy and Corticobasal Syndrome.Eur J Neurol,2010.[Epub ahead of print].
-
7Vidal JS,Vidailhet M,Derkinderen P,et al.Familial aggregation in atypical Parkinson's disease:a case control study in multiple system atrophy and progressive supranuclear palsy.J Neurol,2010,257:1388-1393.
-
8Ros R,Gómez Garre P,Hirano M,et al.Genetic linkage of autosomal dominant progressive supranuclear palsy to 1q31.1.Ann Neurol,2005,57:634-641.
-
9Cruchage C,Vidal-Taboada JM,Ezquerra M,et al.5'-Upstream variants of CRHR1 and MAPT genes associated with age at onset in progressive supranuclear palsy and cortical basal degeneration.Neurohiol Dis,2009,33:164-170.
-
10Ezquerra M,Pastor P,Gaig C,et al.Different MAPT haplotypes are associated with Parkinson's disease and progressive supranuclear palsy.Neurobiol Aging,2009.[Epub ahead of print].
二级参考文献40
-
1Ryman D,Lamb BT.Genetic and environmental modifiers of Alzheimer's disease phenotypes in the mouse.Curr Alzheimer Res,2006,3:465-473.
-
2Mayeux R.Gene-environment interaction in late-onset Alzheimer disease:the role of apolipoprotein-epsilon 4.Alzheimer Dis Assoc Disord,1998,12 Suppl 3:10-15.
-
3Kamboh MI,Sanghera DK,Aston CE,et al.Gender-specific nonrandom association between the alpha 1-antichymotrypsin and apolipoprotein E polymorphisms in the general population and its implication for the risk of Alzheimer's disease.Genet Epidemiol,1997,14:169-180.
-
4Borroni B,Grassi M,Agosti C,et al.Genetic correlates of behavioral endophenotypes in Alzheimer disease:role of COMT,5-HTTLPR and ApoE polymorphisms.Neurobiol Aging,2006,27:1595-1603.
-
5Steiner H,Haass C.Intramembrane proteolysis by presenilins.Nat Rev Mol Cell Biol,2000,1:217-224.
-
6Cirrito JR,Kang JE,Lee J,et al.Endocytosis is required for gynaptic activity-dependent release of amyloid-beta in vivo.Neuron,2008,58:42-51.
-
7Koo EH,Squazzo SL.Evidence that production and release of amyloid beta-protein involves the endocytic pathway.J Biol Chem,1994,269:17386-17389.
-
8Hardy J,Selkoe DJ.The amyloid hypothesis of Alzheimer's disease:progress and problems on the road to therapeutics.Science,2002,297:353-356.
-
9Etcheberrigaray R,Tan M,Dewachter I,et al.Therapeutic effects of PKC activators in Alzheimer's disease transgenic mice.Proc Natl Acad Sci USA,2004,101:11141-11146.
-
10Hwang EM,Kim SK,Sohn JH,et al.Furin is an endogenous regulator of alpha-secretase associated APP processing.Biochem Biophys Res Commun,2006,349:654-659.
共引文献7
-
1唐红梅,白雪.阿尔茨海默病发病机制及治疗研究进展[J].新疆医科大学学报,2010,33(12):1455-1457. 被引量:8
-
2靳淼,安红梅.阿尔茨海默病的动物模型制备及药物治疗[J].神经药理学报,2011,1(6):28-36. 被引量:3
-
3宫志华,孙龙,赵晓娟,张淑玲,宫少青,王晶,于华.人参皂苷Rg2抗拟缺血再灌注损伤大鼠海马神经细胞β_(1-40)淀粉样蛋白聚集研究[J].中华老年心脑血管病杂志,2014,16(1):78-80. 被引量:11
-
4刘婧,付小梅,吴建华,黄潇,关志宇.中药治疗老年痴呆的研究进展[J].中国医药科学,2014,4(11):43-46. 被引量:10
-
5陶冶,俞春江.RNA干扰调节β分泌酶治疗阿尔茨海默病[J].中国临床神经科学,2015,23(3):338-343. 被引量:2
-
6钟汝佳,陶定波,乐卫东.血管性痴呆病因及发病机制的研究进展[J].转化医学杂志,2015,4(4):193-198. 被引量:27
-
7李帅,曹子成.老年性痴呆的发病机制及治疗研究进展[J].云南中医中药杂志,2018,39(3):84-87. 被引量:9
同被引文献34
-
1侯静,陈彤,张晓红,吴卫平,王振福,郭瑞表.103例国人进行性核上性麻痹患者的临床特征[J].神经病学与神经康复学杂志,2010,7(3):135-141. 被引量:14
-
2Litvan I. Progressive supranuclear palsyff Litvan I. Atypical parkinsonian disorders: clinical and research aspects. New Jersey: Humana Press, 2005 : 287-308.
-
3Burn DJ, Lees AJ. Progressive supranuelear palsy: where are we now. Lancet Neurol,2002,1 : 359-369.
-
4Litvan I,Bhatia KP, Burn DJ, et al. Movement Disorder Socie- ty Scientific Issues Committee report: SIC Task Force ap- praisal of clinical diagnostic criteria for Parkinsonian disor- ders. Mov Disord, 2003,18 : 467-486.
-
5Oba H, Yagishita A, Terada H, et al. New and reliable MRI diagnosis for progressive supranuclear palsy. Neurology, 2005,64(12) :2050-2055.
-
6Righini A, Antonini A, De Notaris R, et al. MR imaging of the superior profile of the midbrain: differential diagnosis be- tween progressive supranuclear palsy and Pakinson disease. Am J Neuroradiol, 2004,25 (6):927-932.
-
7Santens P, Sieben A, De Letter M. Repetitive transeranial magnetic stimulation in patients with progressive supranucle- ar palsy: a pilot study. Aete Neural Belg, 2009,109:200-204.
-
8Zampieri C, Di Fabio RP. Improvement of gaze control after balance and eye movement training in patients with progres- sive supranuclear palsy: a quasi-randomized controlled trial. Arch Phys Med Rehabil, 2009,90 : 263-270.
-
9Liepeh I, Gaenslen A, Godan J, et al. Rivastigmine for the treatment of dementia in patients with progressive supranu- clear palsy: clinical observations as a basis for power calcula- tions and safety analysis. Alzheimers Dement, 2010,6 : 70-74.
-
10中华医学会老年医学分会老年神经病学组额颞叶变性专家共识撰写组.额颞叶变性专家共识.中华神经科杂志,2014.47:351-356.
引证文献3
-
1栗晓宏,王展,冯涛,李鑫.进行性核上性麻痹的临床特征及头部磁共振特点[J].山西医药杂志(下半月),2013,42(8):910-912. 被引量:3
-
2陈健华,张莹,高晶,董立羚,崔丽英.进行性精神行为异常一年余 反复跌倒一年并进行性加重[J].中国现代神经疾病杂志,2016,16(7):455-461. 被引量:1
-
3刘俊,李彬,王麟鹏,杨清玄,陈志刚,刘银霞,王春琛.王乐亭“督脉十三针”治疗进行性核上性麻痹临床观察[J].北京中医药,2020,39(5):496-498. 被引量:5
二级引证文献8
-
1段凌云,徐军,石卉.“王氏夹脊穴”合“督脉十三针”逆针灸治疗中风后痉挛性瘫痪疗效观察[J].四川中医,2023,41(2):213-216. 被引量:5
-
2王成银,黄坚红.进行性核上性麻痹2例报道并文献复习[J].中华全科医学,2018,16(1):160-163. 被引量:1
-
3陈敏.磁共振帕金森综合征指数对进行性核上性麻痹预后的临床价值[J].中国医药指南,2020,18(6):98-99. 被引量:1
-
4史梦楠,李波,董健健,徐陈陈,程楠,韩永升,韩咏竹.自噬在中医药治疗运动障碍疾病的作用研究概况[J].中医药临床杂志,2021,33(7):1410-1414.
-
5师志霞,王瑞,周梦媛,赵因,王桂玲.金针王乐亭治疗截瘫经验撷萃[J].中国医药导报,2022,19(2):134-137. 被引量:2
-
6梁肖迪,周润津,曾婧纯,皮立宏,林兴栋,肖璐.167例进行性核上性麻痹患者的临床特征及诊治分析:近十年文献分析[J].实用心脑肺血管病杂志,2022,30(5):89-94. 被引量:1
-
7黄蒙蒙,邵薇,牛红月.醒脑开窍针法结合芒针透刺法治疗进行性核上性麻痹验案[J].实用中医药杂志,2022,38(7):1254-1255. 被引量:2
-
8颜蕊,吴伊冰,孙小花,倪江涛,冶尕西.冶尕西运用内热针治疗强直性脊柱炎经验[J].中国民间疗法,2025,33(2):43-46.
-
1揣兰香.进行性核上性麻痹误诊为帕金森病[J].临床误诊误治,2014,27(7):61-61. 被引量:1
-
2华洁.进行性核上性麻痹误诊为帕金森病[J].临床误诊误治,2005,18(3):198-198. 被引量:1
-
3刘玥,刘芳.进行性核上性麻痹认知功能损害2例[J].贵阳医学院学报,2012,37(6):695-696. 被引量:2
-
4孟祥武,唐荣华,陈兴泳,胡伟,王晖.进行性核上性麻痹2例报道[J].神经损伤与功能重建,2009,4(2):149-150. 被引量:2
-
5朱银伟,孙永安,陈俊,肖朝勇,时建铨,张楚楚,江炜炜,张颖冬,徐俊.磁共振帕金森综合征指数在进行性核上性麻痹预后中的价值[J].中华老年心脑血管病杂志,2013,15(3):273-276. 被引量:7
-
6王艳萍,楚红云,路彦生,高凤琴.进行性核上性麻痹1例[J].吉林医学院学报,1996,16(1):22-22. 被引量:1
-
7潘庆宏,冯兆磊,罗音,梁兰,梅华,徐建凡,周玉珍.甘露醇对自发性脑出血预后的不良影响(附525例前瞻性研究及352例回顾性分析)[J].临床神经病学杂志,2000,13(3):149-151. 被引量:13
-
8于逢春,朱静.急性脑卒中患者的医院感染308例分析[J].中华医院感染学杂志,2000,10(1):34-35. 被引量:20
-
9震颤麻痹综合征[J].国外科技资料目录(医药卫生),2002(9):167-167.
-
10侯静,张晓红,陈彤,孙虹,王振福.原发性进行性冻结步态[J].中华老年心脑血管病杂志,2009,11(7):521-522. 被引量:1