摘要
由于细菌对抗生素耐药性不断出现,研发新型抗菌药物已迫在眉睫。抗菌肽是一种广泛存在于生物体内具备多生物活性的小分子多肽,其独特的抗菌机制和细菌不易对其产生耐药性,已倍受人们关注。论文对抗菌肽来源、分类以及生物特性、相关数据库基本情况、存在的问题等方面研究进展进行综述。
Along with the advent of resistance to antibiotics,the development of new antimicrobial agents is a matter of great urgency.The special antibacterial mechanism of antibacterial peptide doesn＇t make bacteria to become resistant easily.Antibacterial peptide is a kind of minor polypeptides which widely distributed in organism with multi-bioactivity.The studies on the antimicrobial peptide drew more and more attention.This paper gave a review to the research of antimicrobial peptides,including source,classification,bio-characteristics,related database and existing problems.
出处
《动物医学进展》
CSCD
北大核心
2011年第3期94-99,共6页
Progress In Veterinary Medicine
基金
湖南省科技厅科技科研项目(2010NK3015)
湖南农业大学大学生创新性实验计划项目(YCX1020)
关键词
抗菌肽
生物特性
小分子多肽
耐药性
antibacterial peptide
biological property
minorpolypeptide
drug resistance
