摘要
目的评估颈内静脉血氧饱和度（SjvO2）作为重型颅脑损伤的预后指标可能性及其与脑灌注压（CPP）的相关性。方法重型颅脑损伤病人52例，每6h测定一次SjvO2持续监测平均动脉压及颅内压，计算出CPP，分析SjvO2与预后的相关性。结果在监测期间有2次或2次以上SjvO2〈50％或SjvO2〉75％者预后良好率明显低于SjvO2 50％-75％者或仅有一次SjvO2〈50％或SjvO2〉75％者（P〈0．01）。CPP≤60mmHg者，SjvO2与CPP显著正相关（r=0．679，P〈0．01），而CPP〉60mmHg者，SjvO2与CPP无明显相关（P〉0．05）。结论SjvO2和CPP联合监测能较可靠地预测重型颅脑损伤患者的预后。
Objective To explore the possibility of jugular vein blood oxygen saturation （SjvO2） serving as indicators of prognosis and its relationship with the cerebral perfusive pressure （CPP） in the patients with severe traumatic brain injury （sTBI）. Methods The SjvO2 was determined every 6 hours, the mean arterial pressure （MAP） and intracranial pressure（ICP） were continuously monitored in 52 patients with sTBI. CPP was calculated. The relationship of SjvO2 and CPP with the prognosis was analyzed in all the patients. Results The rate of the good prognosis in the patients who had 2 or more than 2 times SjvO2〈50% or 〉75% was significantly lower than that in the patients who had 50%-75% SjvO2 or only 1 time SjvO2〈50% or 〉75% during monitoring SilO2 （P〈0.01）. The CPP was positively related to SjvO2 in the patients with CPP〈60 mmHg （P〈0.01） and not to the SjvO2 in the patients with CPP≥60 mmHg （P〉0.05）. Conclusion SjvO2 combined with CPP may be reliable to predict prognosis in the patients with sTBI.
出处
《中国临床神经外科杂志》
2011年第2期72-74,共3页
Chinese Journal of Clinical Neurosurgery
关键词
重型颅脑损伤
脑灌注压
颈内静脉血氧饱和度
预后
Severe traumatic brain injury
Jugular vein
Blood oxygen saturation
Cerebral perfusion pressure
Prognosis
