摘要
目的总结糖皮质激素致重症水痘的临床特点,探讨其防治对策。方法对2002年8月—2009年8月住院的20例糖皮质激素致重症水痘临床资料进行回顾性分析。结果糖皮质激素致重症水痘主要以儿童为主。少数病例临床表现不典型。本组20例中误诊2例(10.00%),其与首诊误诊、大剂量应用糖皮质激素有关。20例重症水痘患者19例治愈,1例死亡。结论水痘患者不宜应用糖皮质激素治疗。因原有疾病长期应用糖皮质激素治疗的水痘患者应尽快将糖皮质激素减至生理剂量。应加强抗感染、增强免疫力及支持治疗。
Objective To summarize the clinical characteristics of glucocorticoid-induced severe varicella, and to investigate the strategies for its prevention and treatment. Method The clinical data of 20 in-patients with glucocorticoid-induced severe vari- cella treated from Aug. 2002 to Aug. 2009 were retrospectively analyzed. Results The majority of these patients with glucocorticoid- induced severe varicella were children, and a few had atypical clinical manifestations. Two patients （10.00%） were misdiagnosed and the misdiagnosis was associated with initial misdiagnosis and administration of high-dose glucocorticoids. Of the 20 patients, 19 were cured and 1 died. Conclusions Patients with varicella should not be treated with glucocorticoids. The dose of glucocorticoids should be reduced to physiological dose in the patients with varicella who have received lone-term glucocorticoid therapy due to underlying diseases. It is important to improve immunity and enhance anti-infection and support treatment.
出处
《传染病信息》
2011年第1期41-43,共3页
Infectious Disease Information
关键词
重症水痘
糖皮质激素类
临床分析
severe varicella
glucocorticoids
clinical analysis
