摘要
目的了解揭阳市人民医院2009年临床分离菌对常见抗生素的耐药情况。方法药敏试验用K-B纸片法,根据2003年美国临床实验室标准化委员会(NCCLS)标准判断结果,应用WHONET5.3软件对临床分离细菌的药敏结果进行统计分析。结果临床分离717株细菌中G+球菌有219株(30.54%),G-杆菌有498株(69.46%);耐甲氧西林金黄色葡萄球菌(MRSA)和耐甲氧西林凝固酶阴性葡萄球菌(MRCNS)分别占80.56%和88.43%,尚未监测到万古霉素耐药的葡萄球菌;肠球菌对万古霉素耐药率达19.23%。大肠埃希菌对亚胺培南有较高敏感率,铜绿假单胞菌对亚胺培南的耐药率为12.5%。结论揭阳市人民医院细菌耐药性监测结果,对指导我地区临床合理应用抗菌药物和减缓细菌耐药有重要意义。
Objective To investigate the drug resistance of clinical isolates from the People’s Hospital of JieYang in 2009.Methods Antimicrobial susceptibility tests of clinical isolates were performed using Kirby-Bauer methods and the results were evaluated based on the standards recommended by NCCLS （2003）.The data were analyzed by using WHONET-5.3 software.Results Of 717 clinical isolates,Gram positive organisms accounted for 219（30.54%）,Gram negative organisms for 498（69.46%）.The detection rates of MRSA and MRCNS were 80.56% and 88.43% respectively,no vancomycin resistant strains were found.The resistance of Vancomycin to Staptococcus was 19.23%.Isolate of E.coli was susceptible to imipenem.However,pseudomonas aeruginosa were resistant to imipenim,its resistance rate was 12.5%.Conclusion Surveillance data of bacterial reistance was important and valuable for the guidance of rational selection of antimicrobial agents to treat bacterial infection nosocomially.
出处
《当代医学》
2011年第10期7-8,共2页
Contemporary Medicine
关键词
细菌耐药性
药物敏感性试验
监测
Bacterial resistance
Drug susceptibility test
Surveillance
