期刊文献+

肠道病毒感染在小儿原发性肠套叠发病中的作用 被引量:5

The role of enterovirus infection in children with idiopathic intussusception
在线阅读 下载PDF
导出
摘要 目的探讨肠道病毒感染在儿童肠套叠发病中的地位,为临床预防和减少肠套叠的发生提供理论依据。方法研究组为首都医科大学附属北京儿童医院2002年9月至2003年12月确诊的72例原发性肠套叠患儿,以时间、年龄及性别匹配的78例健康儿童为对照组,分别采集粪便标本。使用肠道病毒公用引物进行逆转录聚合酶链反应,检测粪便标本中的肠道病毒。结果研究组和对照组肠道病毒的阳性率分别为2.8%(2/72)和3.8%(3/78),两组间差异无统计学意义(P>0.05)。结论肠道病毒感染与原发性肠套叠之间可能无相关性。 Objective To find the relationship among enterovirus infection and idiopathic intussusception. Methods Fecal and blood samples were collected from 72children with idiopathic intussusception that was observed in Beijing Children's Hospital. Additional samples of 78 time-age-and sex-matched healthy children collected from September 2002 to December 2003 were enrolled in this study as controls. Results transcriptase polymerase chain reaction(RT-PCR) were used to detect rotavirus and enterovirus in fecal samples respectively. Results Enterovirus was observed in 2 of 72 patients (2.8%) and 3 of 78 control children (3.8%). There was no significant difference between two groups (P0.05). Conclusions The data of the present study suggest that enteroviral infection may not be association with intussusception.
出处 《中国妇幼卫生杂志》 2011年第2期64-66,共3页 Chinese Journal of Women and Children Health
基金 国家自然科学基金资助项目(编号:30371474)
关键词 肠道病毒 儿童 肠套叠 Enterovirus Children Intussusception
  • 相关文献

参考文献9

  • 1金先庆,伍烽,雷培芸,许嘉陵,陈志远.胃泌素在婴幼儿肠套叠发病中的作用[J].中华外科杂志,1996,34(2):92-94. 被引量:11
  • 2步星耀,金百祥,沈兆忠,王淑萱.小儿肠套叠与肠道病毒感染[J].中华小儿外科杂志,1995,16(6):346-348. 被引量:54
  • 3N. Andrews,E. Miller,P. Waight,P. Farrington,N. Crowcroft,J. Stowe,B. Taylor.Does oral polio vaccine cause intussusception in infants? Evidence from a sequence of three self-controlled cases series studies in the united kingdom[J]. European Journal of Epidemiology . 2001 (8)
  • 4Miguel A. Galindo Sardi?as,Andrés Zambrano Cárdenas,Gisele Coutin Marie,Manuel Santin Pe?a,Miriam Ali?o Santiago,Marlen Valcárcel Sanchez,C.P. Farrington.Lack of association between intussusception and oral polio vaccine in Cuban children[J]. European Journal of Epidemiology . 2001 (8)
  • 5Tee KK,Lam TT,Chan YF,et al.Evolutionary genetics of human enterovirus71:origin,population dynamics,natural selection,and seasonal periodicity of the VP1gene. Journal of Virology . 2010
  • 6Chia AY,Chia JK.Intestinal intussusception in adults due to acute enterovirus infection. Journal of Clinical Pathology . 2009
  • 7Moral GL,Rubio CE,Broto EP,et al.Enteroviral infections in children: clinical and epidemiological findings in 530 patients (1984-1991). Anales Espanoles de Pediatria . 1993
  • 8Nicolas,JC,Ingrand,D,Fortier,B,Bricout,F.A one-year virological survey of acute intussusception in childhood. Journal of Medical Virology . 1982
  • 9SchlesingerY,SawyerMH,StorchGA.Enteroviralmeningitisininfancy:potentialroleforpolymerasechainreactioninpatientmanagement. Pediatrics . 1994

二级参考文献4

  • 1尤胜义,天津医学,1992年,20卷,654页
  • 2王智,生理科学进展,1986年,17卷,48页
  • 3王志均,胃肠激素,1985年
  • 4李正,中华小儿外科杂志,1984年,5卷,193页

共引文献59

同被引文献82

  • 1步星耀,金百祥,沈兆忠,王淑萱.小儿肠套叠与肠道病毒感染[J].中华小儿外科杂志,1995,16(6):346-348. 被引量:54
  • 2赵长安,周红,李仲智,方肇寅,杨永弘.轮状病毒感染与小儿原发性肠套叠关系探讨[J].中国基层医药,2005,12(7):769-770. 被引量:3
  • 3张丽杰,方安.中国婴幼儿轮状病毒腹泻的流行病学和疾病负担研究进展[J].中国计划免疫,2007,13(2):186-191. 被引量:123
  • 4李焕,刘国庆,谭汝宏,唐华建,白立芳,王剑锋,李杰荣.原发性肠套叠患儿血清柯萨奇病毒IgM检测结果分析[J].临床小儿外科杂志,2007,6(4):43-44. 被引量:2
  • 5Niramis R, Watanatittan S, KruatrachueA, et al. Management of recurrent intu-ssusception: nonoperative or operativereduction [J]. Journal of Pediatric Sur-gery,2010,45: 2175-2180.
  • 6Bines JE,Ivanoff B.Acute intussusception in infants and children:incidence,clinical presentation,and management:a global perspective[M].Geneva:WHO,2002:1-98.
  • 7Konno T,Suzuki H,Kutsuzawa T,et al.Human rotavirus infection in infants and young children with intussusception[J].J Med Virol,1978,2(3):265-269.
  • 8Robinson CG,Schulman MH,Zhu Y,et al.Evaluation of anatomic changes in young children with natural rotavirus infection:is intussusception biologically plausible?[J].J Infect Dis,2004,189(8):1382-1387.
  • 9Steele AD,Patel M,Parashar UD,et al.Rotavirus vaccines for infants in developing countries in Africa and Asia:considerations from a World health organization-sponsored consultation[J].J Infect Dis,2009,200 Suppl 1:S63-69.
  • 10Carlin JB,Macartney KK,Lee KJ,et al.Intussusception risk and disease prevention associated with rotavirus vaccines in Australia's national immunization program[J].Clin Infect Dis,2013,57(10):1427-1434.

引证文献5

二级引证文献44

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部