摘要
目的:探讨冠状动脉造影患者血清尿酸(SUA)水平与冠状动脉病变程度的关系。方法:266例患者根据冠脉造影结果分为对照组(n=79)和冠心病组(n=187),根据冠脉病变支数分为单支病变组、双支病变组和三支病变组。测定各组血清尿酸水平,比较各组患者的血清尿酸水平和血清尿酸与冠脉病变范围的相关性,并分析血UA与冠心病发生之间的关系。结果:UA在冠心病组(399.06±96.32)μmoL/L明显高于对照组(308.45±72.85)μmoL/L,差异有统计学意义(P<0.01)。单支病变组、双支病变组、三支病变组尿酸分别为(386.23±87.04)μmoL/L、(397.76±95.30)μmoL/L、(416.06±80.72)μmoL/L,血尿酸水平呈递增趋势,但三组之间比较差异无统计学意义(P>0.05)。结论:血尿酸水平与冠状动脉病变程度呈正相关。
Objective：To evaluate the relationship between the serum uric acid（SUA） level and the severity of angiographic coronary artery disease（CAD）.Method：We divided 266 patients who underwent coronary angiography into control group（n=79）and coronary atherosclerotic heart disease（CHD） group（n=187） in which patients were,in turn,divided into single-,double-and triple-vessel disease groups according to the number of vessels with significant stenosis.The serum uric acid level was determined,and the serum uric acid levels of different groups and the association between the serum uric acid level and coronary lesions were compared,and investigated the association between serum UA and the presence of CHD.Result：Serum UA level in CHD group,（399.06±96.32）,μmoL/L was significantly higher than that in control group（308.45±72.85） μmoL/L,respectively and the serum uric acid levels between the two groups were significantly different（P〈0.01）.The serum uric acid levels of the single-vessel group,double-vessel group and triple-vessel group were（386.23±87.04）μmoL/L,（397.76±95.30）μmoL/L,（416.06±80.72）μmoL/L,There was a trend of increase of UA level in the three groups,but respectively and the serum uric acid levels in the three groups were no significantly different（P〉0.05）.Conclusion：The level of the UA is positively associated with the severity coronary artery lesion.
出处
《河北医学》
CAS
2011年第5期614-617,共4页
Hebei Medicine
关键词
血尿酸
冠脉造影
冠心病
Serum uric acid； Coronary angiography； Coronary heart disease；
