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帕瑞昔布钠复合舒芬太尼用于甲状腺手术术后镇痛的临床观察 被引量：4

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摘要 目的:观察静脉注射帕瑞昔布钠复合舒芬太尼用于甲状腺手术术后镇痛的有效性和不良反应。方法:择期甲状腺手术患者90例,随机分为两组:实验组于手术缝皮前和晚上9点分别静脉推注帕瑞昔布钠40 mg(生理盐水稀释至5 mL);对照组静脉推注生理盐水5 mL。术毕两组均给予患者自控的静脉镇痛泵术后镇痛,镇痛药配方为舒芬太尼50μg稀释至100 mL。记录术后24 h内镇痛评分(VAS)、镇静评分(Ramsay)、不良反应及术后镇痛满意度。记录24 h舒芬太尼用量。结果:实验组患者术后1、12 h VAS评分显著低于对照组(P<0.05),而两组间Ramsay镇静评分差异无统计学意义(P>0.05)。实验组术后24 h内舒芬太尼使用量显著低于对照组(P<0.01),对照组患者在PCA期间各不良反应的发生率及不良反应发生总例次高于实验组(P<0.01)。两组患者术后满意度差异无统计学意义(P>0.05)。结论:帕瑞昔布钠复合舒芬太尼用于甲状腺手术术后镇痛效果良好,并可减少舒芬太尼的用量及不良反应发生率。
作者 董晓西 刘付丽 施克俭 倪建武 徐旭仲
机构地区 温州医学院附属第一医院麻醉科
出处 《温州医学院学报》 CAS 2011年第2期170-172,共3页 Journal of Wenzhou Medical College
关键词 帕瑞昔布钠 舒芬太尼 甲状腺手术 镇痛
分类号 R653 [医药卫生—外科学]
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二级参考文献24

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共引文献82

同被引文献46

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二级引证文献15

温州医学院学报
2011年 第2期

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