摘要
目的:探讨多囊卵巢综合征合并不孕患者治疗策略的选择及影响因素。方法:选择2005年8月～2009年5月在赣州市人民医院妇产科不孕不育门诊就诊的76例多囊卵巢综合征患者,分研究组(达因-35+二甲双胍预处理组)39例,对照组(直接促排卵组)37例;研究组予达因-35+二甲双胍预处理3～6月,复查血促黄体生成素、睾酮、胰岛素正常后予促排卵,指导同房,对照组直接予促排卵指导同房;观察2组的排卵率、妊娠率、流产率。结果:研究组的排卵率与对照组差异无统计学意义(P>0.05),妊娠率、流产率与对照组差异有统计学意义(P<0.05)。结论:多囊卵巢综合征合并不孕患者经达因-35联合二甲双胍预处理后,可明显提高患者的妊娠率,降低流产率。
Objective：To explore choices and influencing factors of treatment strategies for infertile women with polycystic ovary syndrome（PCOS）.Methods：76 patients with PCOS were selected from Aug,2005 to May,2010 in our hospital,and were divided into study group（39 cases） which were pretreated with Diane-35 and Mefformin and the control group（37 cases） which were inducted ovulation directly without any pretreatments.Luteinizing hormone（LH）,testosterone（T） and insulin in blood were measured after being given Diane-35 and Metformin for three to six months in the study group,and then they were inducted to ovulate and guided to have sexual intercourse when the concentration of LH,T and insulin were at the normal level.The control group were inducted to ovulate directly without any pretreatments and were advised to have sexual intercourse at same time.The rates of ovulation,pregnancy and abortion of the two groups were observed.Results：There were no significant difference in the rate of ovulation between the two groups（P0.05）.The rates of pregnancy and abortion of the study group were significantly different from that of the control group（P0.05,P0.01）.Conclusion：it can improve the rate of pregnancy and decrease the rate of abortion for infertile women with PCOS to be pretreated with Diane-35 and Metformin.
出处
《中国妇幼保健》
CAS
北大核心
2011年第14期2201-2202,共2页
Maternal and Child Health Care of China
