摘要
目的:星点设计-效应面法优选荷叶中总生物碱的提取工艺。方法:以乙醇浓度、料液比、pH值为自变量,荷叶总生物碱的提取率为因变量,运用效应面法优化超声波法提取荷叶总生物碱的工艺条件,并进行预测分析。结果:确定超声波法提取荷叶总生物碱的最佳工艺条件为乙醇浓度80%、料液比1∶75、pH值5。结论:该实验提取工艺方法简便,预测值与实际值吻合度高。
Objective：To optimize the extracting process of Folium Nelumbinis by central composite design and response surface method.Methods：Independent variables were ethanol concentration,solvents ratio and pH,dependent variable was extracting rate of alkaloid.Composite design and response surface method were used to optimize the extracting process.Resultant model was used to predict the response in the optimal region.Results：The optimum extraction conditions were 80% aqueous ethanol,75 fold solvent,pH value 5.Conclusion：The optimum process is simple and more convenient for extracting Folium Nelumbinis.The observed and predicted values are close to each other.
出处
《中药材》
CAS
CSCD
北大核心
2011年第4期616-619,共4页
Journal of Chinese Medicinal Materials
基金
"十一五"国家科技支撑计划项目(2006BAI08B03-04)
关键词
荷叶
总生物碱
星点设计
效应面法
Folium Nelumbinis
Total alkaloid
Central composite design
Response surface method
