摘要
在气/液界面上,阳离子表面活性剂可以通过静电作用与阴离子型的脱氧核糖核酸(DNA)分子形成复合膜,并压缩沉积得到LB(Langmuir-Blodget)膜.利用表面压-表面积(π-A)曲线、原子力显微镜(AFM)和石英晶体18-微s-天18平,s=(Q3,C4M,6),研8,究10了,1阳2)离与子DNGAe(m双in链i表DN面A(活ds性DN剂A()[,C单18H链37D(CNHA3)(2sNsD+-N(CAH))2之)s-N间+的(C相H3互)2C作18用H3,7]·并2对Br1-8,-简s-1写8为在不同下相表面的分子面积进行了比较.实验结果表明连接基团和下相的DNA对Gemini表面活性剂在气/液界面上的性质有很大影响.此外,Gemini表面活性剂在界面上对DNA的吸附能力与它们之间的相互作用方式密切相关.
Monolayers may be obtained by an electrostatic force between cationic surfactants and anionic electrolyte deoxyribonucleic acid （DNA） molecules, and a corresponding Langmuir-Blodgett （LB） complex monolayer can be fabricated by compression and deposition of the monolayer at the air/water interface. In this work, the interaction between cationic Gemini surfactants （[C18H37（CH3）2N＋-（CH2）s-N＋（CH3）2- C18H37]·2Br-, abbreviated 18-s-18, s=3, 4, 6, 8, 10, 12） and double-strand DNA （dsDNA）/single-strand DNA （ssDNA） was investigated by surface pressure-surface area （π-A） isotherms, atomic force microscope （AFM）, and Quartz crystal microbalance （QCM）. Moreover, the limiting molecular areas of 18-s-18 on different subphases were compared. We found that the spacer and the subphase greatly influence the properties of the Gemini surfactants at the air/water interface. In addition, we conclude that the adsorption capacity of the Gemini surfactants with DNA is closely related to their interaction modes.
出处
《物理化学学报》
SCIE
CAS
CSCD
北大核心
2011年第6期1467-1473,共7页
Acta Physico-Chimica Sinica
基金
国家自然科学基金(20806025,20706013)
长江学者创新团队(IRT0721)
教育部留学回国人员科研启动基金
中央高校基本科研业务费资助~~
