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地特胰岛素药理学研究进展 被引量:4

Progress on pharmacology of insulin detemir
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摘要 糖尿病是以胰岛β细胞功能衰减为基本病理生理机制,高血糖为主要代谢紊乱,心脑肾及血管并发症为主要的临床特征的内分泌疾病。患病率高,致残率高,死亡率高,已成为我国重要的公共健康问题。
出处 《武警医学院学报》 CAS 2011年第8期678-681,共4页 Acta Academiae Medicinae CPAPF
基金 武警医学院博士启动基金课题(WBS200905)
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参考文献24

  • 1杨文英.中国人的糖尿病患病率【N].中国医学论坛报(新英格兰医学杂志文章选登),2010,36(10):E1—6.
  • 2Hartmon I. Insulin analogs: Impact on treatment success, satifaction, quality of life, and Adherence[J]. Clin Med Res, 2008, 6(2): 54-67.
  • 3Freeman JS. Insulin analog therapy: improving the match with physiologic insulin secretion[J]. J Am Osteopath Assoc, 2009, 109(1): 26-36.
  • 4Wiesli P, Krayenbuhl P, Uthoff H, et al. Omitting breakfast and lunch after injection of different long-acting insulin preparations at bedtime: a prospective study in patients with type 2 diabetes[J]. Diabetologia, 2009, 52(9): 1816-1819.
  • 5Raslova K. An update on the treatment of type 1 and type 2 diabetes mellitus: focus on insulin detemir, a long-acting human insulin analog[J]. Vasc Health Risk Manag, 2010, 1 (6):399-410.
  • 6Blonde L, Merilainen M, Karwe V, et al. Patient-directed titration for achieving glyeaemic goals using a once-daily basal insulin analogue: an assessment of two different fasting plasma glucose targets-the TITRATE study[J]. Diabetes Obes Metab, 2009, 11(6): 623-631.
  • 7Meneghini L, Liebl A, Abrahamson MJ. Insulin detemir: A historical perspective on a modern basal insulin analogue[J]. Prim Care Diabetes, 2010, 4(Suppl 1): S31-42.
  • 8Fogelfeld L, Dharmalingam M, Robling K, etal. A randomized, treat-to-target trial comparing insulin lispro protamine suspension and insulin detemir in insulin-naive patients with Type 2 diabetes[J]. Diabet Med, 2010, 27(2): 181-188.
  • 9Chacra AR, Kipnes M, Ilag LL, et al. Comparison of insulin lispro protamine suspension and insulin detemir in basal-bolus therapy in patients with Type 1 diabetes[J]. Diabet Med, 2010, 27(5): 563-569.
  • 10Swinnen SG, Dain MP, Aronson R, et al. A 24-week, randomized, treat-to-target trial comparing initiation of insulin glargine once-daily with insulin detemir twice-daily in patients with type 2 diabetes inadequately controlled on oral glucose-lowering drugs[J]. Diabetes Care, 2010, 33(6): 1176-1178.

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