摘要
目的探讨女性原发性高血压患者绝经前后血脂的变化及其意义。方法将80例女性原发性高血压患者分为绝经前组和绝经后组,测定晨起空腹静脉血中总胆固醇(TC)、三酰甘油(TG)、低密度脂蛋白胆固醇(LDL-C)、高密度脂蛋白胆固醇(HDL-C),将各指标与健康对照组以及高血压患者绝经前后对比分析。结果高血压组TC、TG、LDL-C显著高于对照组,差异均有统计学意义(P<0.05),而HDL-C、HDL-C/TC则明显低于对照组,差异均有统计学意义(P<0.05)。高血压组绝经前HDL-C、HDL-C/TC高于绝经后组,差异均无统计学意义(P<0.05),TC、TG、LDL-C低于绝经后组,差异均有统计学意义(P<0.05)。结论女性原发性高血压患者绝经后TC、TG、LDL-C增高,而HDL-C、HDL-C/TC降低,提示绝经后女性原发性高血压患者应注意加强追踪检查血脂成分的测定。
Objective To observe the changs of serum lipid levels in women with essential hypertension before and after menopausal its clinical significance. Methods 80 female with essential hypertension were divided into premenopausal group and post menopausal one. The total cholesterol （TC）, triglycerides （TG）, low density lipoprotein chelesterol（LDL-C）and high density lipoprotein chelesterol（HDL-C） in those groups were tested,and the result was compared between the hypertensive groups and the control group,as well as between pre and post-menopausal sub groups. Results Compared with control group,the levels of TC,TG and LDL-C in hypertensive groups were signifi cantly higher （all P〈0.05） ,the levels of HDL-C and HDL C/TC were lower（all P〈0.05）. The levels of HDL C, HDL-C/TC in pre-menopausal group were higher than those of post-menopausal one （all P〈0.05）, but the levels of TC,TG,I.DL C were lower than those of post menopausal one （all P〈0.05）. Conclusion The levels of TC,TG, LDL-C in post menopausal of women with essential hypertension increase, while the levels of HDL-C/TC decrease af ter menopause,which indicate that we should test the boold lipid component of women with essential hypertension before and after menopause.
出处
《检验医学与临床》
CAS
2011年第11期1292-1293,共2页
Laboratory Medicine and Clinic
基金
广东省深圳市科技计划课题(200602073)
关键词
原发性高血压
血脂
绝经
essential hypertension
blood lipid
menopause
