摘要
目的:观察奥美拉唑联合莫沙必利治疗反流性食管炎(RE)的临床疗效,探讨药物治疗反流性食管炎的有效方法。方法:选择反流性食管炎患者112例,随机均分为观察组和对照组,观察组采用奥美拉唑联合莫沙必利治疗,4周后统计2组患者的临床疗效及用药不良反应。结果:治疗4周后,2组患者总有效方面比较具有统计学意义(P<0.05);不良反应方面比较均无显著性差异(P>0.05),且不良反应均为一过性。结论:药物治疗RE时,应选择奥美拉唑联合莫沙必利治疗,可提高临床疗效。
OBJECTIVE：To evaluate the clinicalefficacyofomeprazole combined mosapride for reflux esophagitis and explore the effective therapy for reflux esophagitis.METHODS：A total of 112 reflux esophagitis cases were equally randomized to either trial group receiving omeprazole plus mosapride or control group.After treatment of 4 weeks,theclinical efficacy and adverse drug reactions in the two groups were recorded.RESULTS：There were statistical significant differences in total effective rate between the two groups after 4-week treatment（P〈0.05）,but the differences in side effects were nonsignificant（P〉0.05）and the adverse drug reactions were transient.CONCLUSION：Treatment of reflux esophagitiswithomeprazole plus mosapride results in improved clinical efficacy
出处
《中国医院用药评价与分析》
2011年第6期556-557,共2页
Evaluation and Analysis of Drug-use in Hospitals of China
