摘要
目的 研究离退休老年人体位性低血压（OH）的患病率及临床特点.方法 通过对2010年广州军区离退休干部体检,筛选出1174例65岁以上的老年患者,对其进行健康问卷普查,并测量卧位及立位后0、2 min血压和心率,并分OH组与非OH组进行比较.OH定义为直立位后3 min内收缩压和（或）舒张压下降≥20/10 mm Hg（1 mm Hg=0.133 kPa）.结果 65岁以上老年OH的患病率为25.6%,直立后即刻收缩压下降≥20 mm Hg和（或）舒张压下降≥10 mm Hg（OH-0）者占21.6%;直立2 min后收缩压下降≥20 mm Hg和（或）舒张压下降≥10 mm Hg（OH-2）者占20.7%.OH组和非OH组高血压、心肌梗死、心力衰竭、缺血性脑卒中、糖尿病的患病率分别为83.1%对68.6%、12.0%对6.4%、13.0%对6.3%、22.3%对16.2%、47.2%对39.2%,OH组均高于非OH组,两组比较差异有统计学意义（P〈0.05）;OH组降压药物治疗率虽稍高于非OH组（88.0%对83.6%）,但差异无统计学意义（P=0.115）;两组使用的降压药物种类也无明显差异.结论 OH在离退休老年人较常见,OH患者高血压、糖尿病、心脑血管疾病的患病率较高,降压药物对OH无明显影响.
objective To determine the prevalence and clinical characteristics of orthostatic hypotension（OH）in the elderly and retired population.Methods A total of 1174 elderly and retired people underwent health screening physical examination in Guangzhou military region were included.The orthostatie blood pressure and heart rate were measured in supine position after resting for more than 5 minutes and at 0 and 2 rain after standing.Subjects were divided into OH positive group and OH negative group.Orthostatic hypotension was defined as 20 mm Hg（1 mm Hg=0.133 kPa）or greater decrease in SBP and/or 10 mm Hg or greater decrease in DBP after standing.Results The prevalence of OH in this cohort was 25.6%at either 0 or 2 min after standing（21.6%or 20.7%respectively）.Incidence of hypertension,myocardial infarction（MI）,heart failure（HF）,ischemic stroke and diabetes was significantly higher in OH positive group than in OH negative group（all P〈0.05）,however,antihypertensive medication was similar between the two groups.Conclusions Orthostatic hypotension is comnlon in the elderly and retired population and is associated with increased risk of hypertension,diabetes mellitus and cardiovascular disease.
出处
《中华心血管病杂志》
CAS
CSCD
北大核心
2011年第5期457-462,共6页
Chinese Journal of Cardiology
基金
广东省2009科技计划（20098030801279）
