摘要
目的探讨脑原发性淋巴瘤的MRI表现特征,以提高对该病诊断的准确性。资料与方法回顾性分析11例经病理证实为脑原发性淋巴瘤的数目、部位、信号、强化方式、水肿、占位效应、扩散加权成像(DWI)及磁共振波谱(MRS)表现。结果单发3例(27%),多发8例(73%)。21个(63%)病灶位于幕上脑深部白质近脑室旁,7个(21%)病灶位于脑表面,5个(16%)位于幕下。24个(73%)病灶在T1WI上呈稍低信号,18个(55%)在T2WI上呈稍高信号;5个(36%)病灶周围轻度水肿及占位效应,9个(64%)病灶周围有中重度水肿及占位效应;团块状、结节状均匀强化15个(46%),不均匀环状强化8个(24%);3例肿瘤在DWI上呈高信号,氢质子磁共振波谱(1H-MRS)表现为氮-乙酰天门冬氨酸(NAA)峰、肌酸(Cr)峰降低,胆碱(Cho)峰显著升高,见乳酸(Lac)峰和高大脂质(Lip)峰。结论脑原发性淋巴瘤有较为特征的MRI表现,结合DWI、MRS有助于鉴别诊断。
Objective To investigate the MRI features of primary lymphoma in the brain,in order to increase the diagnostic accuracy.Materials and Methods Eleven cases of primary lymphoma proved by pathology were collected in the study.analyzed retrospectively.All the patients underwent conventional MRI,DWI and MRS examination.The data of the lesions included the number,location,signal intensity,contrast enhancement,edema,mass effect were analyzed retrospectively.Results Three cases（27%）had single lesion and 8 cases（73%）had multiple lesions.Twenty-one lesions（63%）were supratentorial tumors and located in the deep white matter abutting the ventricles,7 lesions（21%）located in the surface of brain and 5（16%） involved infratentorial region.Twenty-four lesions（73%）were slightly hypointense on T1WI,18 lesions（55%）were slightly hyperintense on T2WI.Five lesions（36%）had mild edema and mass effect around the tumors,9 lesions（64%）had moderate or severe edema and mass effect.Fifteen lesions（46%） showed mass and nodular homogeneous enhancement and 8 lesions（24%）showed rim enhancement.All the lesions were hyperintense on diffusion weighted imaging（DWI）.Hydrogen MR spectroscopy（1H MRS）showed N acetyl aspartate（NAA） and Creatine（Cr）decreased,Choline（Cho） increased significantly,Lactate（Lac） and high Lipid（Lip）peak showed.Conclusion Primary lymphoma in the brain had some characteristic MRI features,combining with DWI and MRS might helpful in differential diagnosis.
出处
《临床放射学杂志》
CSCD
北大核心
2011年第6期781-784,共4页
Journal of Clinical Radiology
关键词
淋巴瘤
磁共振成像
颅脑
Lymphoma Magnetic resonance imaging Brain
