摘要
目的:探讨老年2型糖尿病患者冠状动脉粥样硬化的影响因素。方法:对45例住院患者的心脏CT、血同型半胱氨酸(HCY)、血脂、冠心病史等指标进行回顾性分析,以冠脉钙化总积分(TCS)是否异常分组,比较两组间的HCY、血脂、冠心病史等指标的差异;并对TCS可能的影响因素做回归分析。结果:TCS异常组的HCY、甘油三酯、冠心病史显著高于TCS正常组,TCS异常组的高密度脂蛋白则低于TCS正常组,两者之间差异有统计学意义(P<0.05),回归分析提示HCY、冠心病史是冠状动脉粥样硬化的影响因素。结论:老年2型糖尿病患者HCY水平可能是冠心病的影响因素,降低HCY水平可能为降低老年糖尿病患者的冠心病发生率带来获益。
Objective To investigate the influencing factors of coronary atherosclerosis in aged patients with type 2 diabetes. Methods Analyze retrospectively on the clinical materials, total coronary artery calcification score （TCS） and serum homocysteine （HCY） of 45 patients. All patients were divided into TCS normal group （TCS 〈 50）and TCS abnormal group （TCS ≥ 50）, compare HCY and other data between the 2 groups, and explore the influencing factors of coronary atherosclerosis. Results HCY, triglyeride and coronary heart disease history are higher in TCS abnormal group than TCS normal group （P 〈 0.05）, HCY and coronary heart disease history are influencing factors of coronary atherosclerosis. Conclusion HCY might be an influencing factor of coronary atherosclerosis in aged patients with type 2 diabetes, decreasing serum HCY might be helpful in preventing coronary heart disease in those people.
出处
《实用医学杂志》
CAS
北大核心
2011年第13期2359-2361,共3页
The Journal of Practical Medicine
