摘要
从3个方面综述了肝素类化合物对肿瘤转移初期的影响:(1)对肿瘤转移相关酶活性的影响;(2)对肿瘤细胞与血管内皮细胞间及血小板间黏附的影响;(3)对新生肿瘤血管形成的影响。低抗凝活性的肝素类化合物作为肿瘤转移治疗中一个安全有效的新疗法,值得进一步研究。
The influences of heparin-like compounds on tumor metastasis are reviewed in three aspects：（1） the influence of the compounds on the enzymes relevant to tumor metastasis;（2） the influence of the compounds on the adhesion of tumor cells to endothelial cells and platelets;（3） the influence of the compounds on the angiogenesis of tumor.Heparin-like compounds with low anticoagulant activity are promising to be developed into a kind of novel tumor metastasis inhibitors.
出处
《食品与药品》
CAS
2011年第7期286-289,共4页
Food and Drug
