摘要
目的:探讨食管癌病人术后早期肠内营养的可行性、安全性和临床疗效。方法:将58例食管癌病人随机分为早期肠内营养(EEN,n=30)组和全肠外营养(TPN,n=28)组,两组均行营养支持8 d。所有病人在手术前1 d、术后第9天分别测定营养指标、免疫指标、肝功能、体重等,并观察肠功能恢复情况、术后并发症、住院费用和住院时间等。结果:所有病人在观察期间无严重并发症。术后第9天,两组病人体重均低于术前,而TPN组病人下降更明显(P<0.05);EEN组病人前清蛋白、转铁蛋白和IgA术后恢复程度明显好于TPN组(P<0.05);TPN组的ALP升高较EEN组明显(P<0.05);EEN组病人肠蠕动功能恢复较快,肛门排气、排便时间明显早于TPN组(P<0.01);平均住院费用、住院时间亦较TPN组少(P<0.01,P<0.05)。结论:食管癌病人术后EEN安全可行,既能改善营养状态,维护和促进胃肠道功能,又能提高机体免疫功能,减少治疗费用。
Objective：To investigate the feasibility,safety and clinical effects of early enteral nutrition in patients with esophageal cancer.Methods：On the first day before surgery,58 patients were randomly divided into EEN group（n=30） and TPN group（n=28）.A series of parameters including nutritional indicators,immune parameters,liver function and body weight were tested before and after nutrition therapy.The recovery of intestinal function,complication,hospital charges and hospital stays were observed simultaneously.Results：Neither mortality nor serious complication of anastomotic leakage occurred in all patients during the period of study.The concentrations of serum prealbumin,transferrin and immunoglobulin A were significantly elevated in EEN group.The recovery of bowel movement,flatus and defecation in EEN group were observed significantly earlier than TPN group.The average length of stay and hospital charges in EEN group were lower than TPN group.Conclusion：Early feeding for esophageal cancer patients is one safety way,which can improve nutritional condition,protect and promote gastrointestinal function,improve immunity and reduce the cost of treatment.
出处
《肠外与肠内营养》
CAS
北大核心
2011年第4期218-220,224,共4页
Parenteral & Enteral Nutrition
关键词
早期肠内营养
肠外营养
食管癌
营养状况
Early enteral nutrition
Total parenteral nutrition
Esophageal cancel
Nutritional status
