摘要
目的探讨C反应蛋白（CRP）、中性粒细胞比例（N％）在慢性阻塞性肺疾病（COPD）急性加重期诊治中的临床意义。方法选择COPD急性加重期患者71例，比较治疗前及症状好转时血清CRP水平、N％动态变化情况，观察上述指标与症状好转天数、住院总天数的相关性。结果（1）CRP、N％水平在症状好转时分别为（15．24±6．24）mg／L和（0．70±0．11），明显低于COPD急性加重期[分别为（58．68±29．36）mg／L和（0．78±0．11）（P〈0．01）]。（2）COPD患者急性加重期N％与症状好转天数（r=0．240，P〈0．05）、症状好转天数与住院总天数之间（r：0．567，P〈0．01）存在相关性。结论血清CRP水平、N％均可作为评价COPD急性加重期患者感染的客观指标，其中N％尚可作为判定COPD急性加重后症状好转时限的可靠指标，其价值优于CRP。
Objective To study the clinical significance of C-reactive protein（CRP） ,neutrophil granulocyte ratio（N% ）in acute exacerbations of hospitalized patients with chronic obstructive pulmonary disease （COPD）. Methods The serum CRP levels, the gross of N% were detected of the same 71 patients with acute exacerbations of COPD before treatment and after getting better. And the correlations among above-mentioned indexes, the days counter before getting better and the days counter during hospitalization were observed. Results （ 1 ） The levels of CRP and N% of patients after getting better were significantly lower than those before treatment（P 〈 0.01 ）. （2）There was a significant correlation between N% and the days counter before getting better（ r = 0.240 ,P 〈 0.05 ） and also a significant correlation between the days counter before getting better and the days counter during hospitalization（ r = 0. 567, P 〈 0.01 ）. Conclusion The serum CRP level and N% were objective markers in estimating pulmonary infection in COPD patients with acute exacerbations. And N% was a reliable indicator of judging the days counter before getting better and better than CRP.
出处
《中国基层医药》
CAS
2011年第13期1747-1749,共3页
Chinese Journal of Primary Medicine and Pharmacy
关键词
肺疾病
慢性阻塞性
C反应蛋白
白细胞计数
Pulmonary disease, chronic obstructive
C-reactive protein
Leukocyte count
