摘要
【目的】探讨2型糖尿病周围神经病变（DPN）的相关临床危险因素。【方法】对180例2型糖尿病患者进行四肢神经传导速度检测，并将其分为DPN组和非DPN组。同时测定患者的空腹血糖、糖化血红蛋白、甘油三酯等指标，对病程、血生化等各指标进行单因素分析，然后进行多因素Logistic回归分析。【结果】在单因素分析中，DPN组的病程、空腹血糖、糖化血红蛋白水平与非DPN组的相比有显著性差异（P〈0．05）。多因素Logistic回归分析显示：病程、糖化血红蛋白与DPN的发病呈正相关（P〈0．05）。【结论】病程与糖化血红蛋白是DPN的高危因素。
[ObjectivelTo discuss the correlation between the clinical risk factors and Diabetic peripheral neuropathy （DPN）. [Methods]Standard sensory and motor nerve conduction studies were performed in 180 patients with type-2 diabetes. They were divided into DPN and non-DPN group according to the results. Fasting blood glucose, glycosylated hemoglobin and triglyceride of the patients were determined ; T-test, Chisquare test and Logistic Regression were used for statistical analysis, [Results]There were significant difference in fasting blood glucose, glycosylated hemoglobin and the course of the disease between DPN and nonDPN groups（ P 〈0.05）. Significant positive correlation of glycosylated hemoglobin as well as the course with DPN was found（ P 〈0. 05）. [Conclusion]The course of the disease and glycosylated hemoglobin were the high-risk factors of DPN in patients with type-2 diabetes.
出处
《医学临床研究》
CAS
2011年第7期1292-1294,共3页
Journal of Clinical Research
