摘要
目的分析药物不良反应发生的特点和规律,为临床合理用药及药物安全性评价提供依据。方法对我院2008年上报的179例药物不良反应情况进行回顾性分析,对引起ADR的药物种类、给药途径、ADR危害程度、在医院科室中的分布情况等进行汇总分类统计。结果 179例ADR报告中,8个月～89岁各年龄组所占百分比分别为11.7%、33.0%、36.3%、19.0%;涉及的药物中抗菌药物居第1位(30.0%),静脉给药是引起ADR的主要给药方式(占70.4%),产生严重危害者占16.2%;门诊(31.3%)、内科病区(22.3%);肿瘤病区(14.0%)是ADR居医院中分布的前3位。结论 ADR的发生与诸多因素相关,应严格履行药物不良反应的监测及上报制度,减少或避免药物不良反应的发生,保障患者用药安全。
Objective To analyze the characteristics of adverse drug reaction （ ADR ） was in order to promote rational clinical drug use and properly evaluate drug safety. Methods All 179 cases ADR of our hospital during 2008 were collected and retrospective analyzed in respect of age distribution, drug species, routes of administration, hazard evaluation and department distribution. Results In the 179 ADR cases, incidence rate in every age group is 11.7% ,33.0% ,36.3%, 19.0% respectively. The first cause of ADR was usage of antibiotic （ 30.0% ）. Intravenous administration （ 70.4% ） was the main pathway. Serious cases was about 16.2% of 179 cases. The first ADR distribution was in out-patient （ 31.3% ）, the second was in in-patient of medical department （ 22.3% ）, and the third was in in-patient of oncology department （ 14.0% ）. Conclusion The occurrence of ADR is affected by many factors. We need strictly monitor and report ADR case in order to reduce or avoid ADR, and to use reasonably safe and effective medications.
出处
《中国现代医生》
2011年第22期63-65,共3页
China Modern Doctor
