摘要
目的观察小剂量肝素治疗妊娠期肌瘤红色变性的疗效。方法选择2000年1月到2010年5月新乡市第四人民医院收治的21例有临床症状的妊娠期肌瘤红色变性患者作为研究对象,对其临床资料进行回顾性分析。21例患者按治疗方法分为研究组12例和对照组9例,均行静脉滴注硫酸镁和抗生素等保守治疗,其中研究组加用小剂量肝素静脉滴注,观察并对比两组的疗效。结果在研究过程中,两组均未发生因肌瘤红色变性所诱发的早产、流产,亦无单纯行急诊肌瘤切除术者。研究组腹痛减轻、腹痛缓解、宫缩消失和体温正常时间均显著短于对照组,组间比较差异有统计学意义(P<0.05)。研究组治疗期间凝血功能检查无明显异常。结论联合应用小剂量肝素治疗妊娠期肌瘤红色变性的效果优于单用硫酸镁和抗生素,值得临床推广使用。
Objective To observe the curative effect of low-dose heparin for the treatment of uterine fibroids with red degeneration in gestational period.Methods Choosed 21 cases of uterine fibroids with red degeneration in gestational period who were treated in our hospital from January 2000 to May 2010 as the objects of study and the clinical data of them were retrospectively analyzed.21 patients were divided into study group with 12 cases and control group with 9 cases,they were treated by conservative treatment like intravenous drip of magnesium sulfate and antibiotics,and patients in study group additional received low-dose heparin,the curative effect of the two groups were observed and compared.Results In the course of study,no patients in two groups occur premature delivery and miscarriage which induced by uterine fibroids with red degeneration,and also had no patients who had simply emergency myomectomy.The time of abdominal pain lighten and release,uterine contraction loss and body temperature normal of study group were significantly shorter than those the control group,the difference between groups was statistically significant（P0.05）.During treatment,the coagulation function test of study group was normal.Conclusions The combination of low-dose heparin for the treatment of uterine fibroids with red degeneration in gestational period is better than single use of magnesium sulfate and antibiotics,it is worthy of clinical use.
出处
《医药论坛杂志》
2011年第13期67-68,71,共3页
Journal of Medical Forum
关键词
妊娠期
子宫肌瘤
红色变性
肝素
Gestational period
Uterine fibroids
Red degeneration
Low-dose heparin
