摘要
目的探讨肾原发性平滑肌肿瘤的临床特征、组织来源、形态学、免疫表型特点及鉴别诊断。方法对2例肾平滑肌瘤及2例肾平滑肌肉瘤进行常规HE染色及免疫组化染色,并结合临床资料对其临床病理特征进行分析。结果 4例肾平滑肌肿瘤组织学及免疫组化染色均显示平滑肌源性肿瘤特点,其中平滑肌瘤瘤细胞形态温和,平滑肌肉瘤则恶性生物学特征。2例肾平滑肌瘤患者术后生存良好;1例肾平滑肌肉瘤患者术后复发,1例失访。结论肾原发性平滑肌肿瘤罕见,诊断需要结合临床、组织形态及免疫表型,并与肾其他良、恶性肿瘤鉴别。肾平滑肌瘤预后好,平滑肌肉瘤预后较差。
Objective To study the clinicopathological characteristics,etiology and differential diagnosis of primary smooth muscle tumor of the kidney by presenting four new cases and a review of literature.Methods Two cases of leiomyoma and two cases of leiomyosarcoma were studied by routine HE,immunohistochemical staining,together with review of the literature.Results Four cases of renal smooth muscle tumor showed the characteristics of smooth muscle cells by HE and immunohistochemical staining,the leiomyoma of the kidney had a moderate feature,and the leiomyosarcoma was of malignant behaviors.Follow-up showed that postoperative survival of two renal leiomyoma cases were good;one case of renal leiomyosarcoma had a recurrence,and 1 case was missed.Conclusion Primary smooth muscle tumor of the kidney is rare,which requires a combination of clinical,histological and immunohistochemical features to make differential diagnosis from other benign and malignant tumors of the kidney.The prognosis of the leiomyoma is good,but leiomyosarcoma has a poor prognosis.
出处
《诊断病理学杂志》
CSCD
2011年第4期245-248,共4页
Chinese Journal of Diagnostic Pathology
