摘要
本文对41名妇女43个月经周期,分三组进行研究。使用盆腔超声监测排卵指导不孕症的临床治疗,同时辅以放射免疫测定血清雌二醇、孕酮和促黄体生成激素,对20个周期作了子宫腔内人工授精治疗。结果37个周期有排卵,6个周期为无排卵周期。比较三组排卵前最大卵泡直径无显著性差异。将排卵前卵泡直径与血清雌二醇值作直线相关分析,三组均为正相关。试验结果妊娠率为19.3%,人工授精受孕率为20%。我们初步体会:超声监测用药物诱发排卵及自然排卵的卵泡大小、数目、部位与排卵日及指导不孕症的人工授精治疗是可行的。
Fourty three menstrual cycles of 41 women were divided into three groups.The monitoring of ovula- tion with real—time ultrasound(USS)was used to guide the clinical treatment of infertility.Meanwhile, serum estradiol(E_2),progesterone(P_0)and luteinizing hormone(LH)were assayed(RIA).There were 6 anov■latory cycles.Intrauterine insemination(IUI)were performed in 20 cycles.Comparison of the largest follicular diameter 24 hours before ovulation showed no significant disparity between the three groups.Sig- nificant,correlation were found retrospectively between preovulation serum E_2 levels and the largest follicu- lar diameter(γ_n=0.820 1,P<0.025;γ_b=0.924 I,P<0.005;γ_o=0.966 7,p<0.001).The corrected pregnancy rate was 19.3% and the IUI success rate was 20%.The result indicated that USS was practical in confirming the size of follicle,the number of follicles and their location,thence it can be used as a definite measure for detecting ovulation with clomiphene induction and selecting the date of IUI.
关键词
排卵监测
人工授精
不育症
monitoring of ovulation
artifical inscmination
ultrasonography
infertility
clomiphene
