摘要
目的观察壳聚糖宫颈抗菌膜联合宫颈环形电切术(loop electrosurgical excision procedure,LEEP)治疗宫颈病变的临床效果。方法选择宫颈病变100例,随机分为观察组和对照组各50例。观察组予LEEP术后采用壳聚糖宫颈抗菌膜局部用药;对照组仅采用LEEP治疗,观察两组术后阴道排液、脱痂期阴道出血及宫颈创面愈合情况。结果 LEEP术后1～2 d观察组阴道排液明显增多率高于对照组,差异有统计学意义(P<0.05)。两组均于术后7～15 d出现不同程度阴道出血,两组极少量出血与多于月经量出血的发生率比较差异有统计学意义(P<0.05);治疗后观察组不同阴道出血时间发生率与对照组比较差异有统计学意义(P<0.01)。观察组术后1、2、3个月创面治愈率明显高于对照组,差异均有统计学意义(P<0.01)。结论 LEEP术后局部应用壳聚糖宫颈抗菌膜具有减少创面感染、渗出、出血和促进创面愈合的作用。
Objective To observe the effect of antibiotic chitosan membrane combined with loop electrosurgical excision procedure（LEEP） in treatment of cervical diseases.Methods 100 patients with cervical diseases were randomly divided into observation group and control group（50 in each group）.The observation group received antibiotic chitosan membrane after LEEP,but the control group only received LEEP.Vagina apocenosis and bleeding and healing of raw surface in both groups were observed.Results The significant increased rate of vagina apocenosis in the observation group was higher than that in the control group 1-2 days after LEEP,and the difference was significant（P〈0.05）.Both groups had vagina bleeding 7 to 15 days after LEEP,and the rates of thimbleful bleeding and above normal menstrual blood volume between the two groups showed significant difference（P〈0.05）.There was significant difference of the rates of different bleeding times between the two groups（P〈0.01）.The healing rates in observation group were all higher than those in the control group 1,2,and 3 moths after LEEP,and the differences were significant（P〈0.01）.Conclusion Administration of antibiotic chitosan membrane after LEEP can reduce infection on raw surface,effusion,and bleeding and improve healing effect.
出处
《临床误诊误治》
2011年第9期23-25,共3页
Clinical Misdiagnosis & Mistherapy
关键词
壳聚糖
宫颈环形电切术
宫颈疾病
宫颈上皮内瘤样病变
Chitosan
Loop electrical excision procedure
Cervix disease
Cervical intraepithelial neoplasia
