摘要
目的:评价两种结核病抗体快速检测试剂盒在结核病辅助诊断中的价值。方法:用两种已获临床批文的结核病抗体检测试剂盒对216例血清标本进行检测,并对其中69例肺结核患者进行痰涂片检查,将检测结果进行比较分析。结果:试剂盒1和试剂盒2对113例结核血清标本的检出率分别为80.53%和79.65%,差异无统计学意义(P>0.05);对53例非结核疾病组的检出率分别为30.19%和18.87%,差异有统计学意义(P<0.05);两种试剂盒对50例健康对照标本的检出率均为10%,差异无统计学意义(P>0.05);69例肺结核患者痰涂片阳性率为27.5%。结论:两种试剂盒在结核病筛查和辅助诊断中可以互用,联合使用有助于提高结核病的检出率。
Objective： To evaluate the clinical value of two tuberculosis（TB） antibody detection kits on the auxiliary diagnosis of tuberculosis.Methods： 216 human sera were detected the anti-TB antibodies by the two commercial TB antibody detection kits,69 pulmonary tuberculosis were detected by sputum smear,and the performance of the kits were evaluated.Results： The positive rate of kit 1 and kit 2 were 80.53% and 79.65% in TB group,both were 10% in healthy control group;30.19% and 18.87% in non-TB disease group,which had significant difference（P〈0.05）.The sputum smear-positive rate of pulmonary tuberculosis was 27.5%.Conclusion： The two kits can be used in the screening or auxiliary diagnosis of TB,the combined use of two kits can improve detection rate of TB.
出处
《中国医药导报》
CAS
2011年第28期129-130,共2页
China Medical Herald
基金
国家重大传染病防治科技重大专项基金资助项目(2008ZX10003-001)
北京市科技计划研发攻关类科研基金资助项目(D08050700640802)
关键词
结核
抗体
快速检测
辅助诊断
Tuberculosis
Antibody
Rapid detection
Auxiliary diagnosis
