摘要
目的探讨糖尿病和高血压病在骨质疏松的发病过程中的影响及其可能机制。方法 2010年5月～2010年11月期间的门诊和住院病人中选取102名患者,将其分为四组,分别是对照组,糖尿病组、高血压组和糖尿病并高血压病组,对每个患者采用双能X线骨密度仪分别测定其腰椎(L1～4)、左,右侧股骨骨密度,数据以T值方式来记录。结果受试者的年龄在45～68岁之间,其中男女年龄相近,女性比男性T值低(P<0.05),糖尿病组、高血压组和糖尿病并高血压病组T值比对照组低(P<0.05),糖尿病组与糖尿病并高血压病组比较除男性右股骨T值低(P<0.05)外,其他部位两组间无明显差异(P>0.1)。结论糖尿病对骨量减少有明显的影响,糖尿病合并高血压不增加骨量流失,与男性相比女性更易发生骨质疏松。
Aim To explore the effects of diabetes and high blood pressure on bone mass.Methods From May to November in 2010,102 patients,selected from outpatients and inpatients,were divided into four groups： controls,diabetes,hypertension and diabetes associated with hypertension.Bone mineral density（BMD） of lumbar（L1~4）,left and right femur of each patient were measured by dual-energy X-ray absorptiometry（DEXA）,dataes were recorded with T values.The diagnosis of bone loss and osteoporosis was made when individual T value was less than-1.0 SD（standard deviation）and-2.5 SD respectively.Results Subjects were between the ages of 45~68 years,of whom men and women were of similar age.T value was lower in women than in men（P0.05）.Patients with diabetes,hypertension and diabetes hypertension associated with hypertension had a lower T value than the controls（P0.05）.Except that the T value of the right femur in men was lower than in women（P0.05）,there were no significant differences of T values between males and females in the other detection regions（P0.1） Conclusions Diabetes have significant influence on bone mass loss,while diabetes associated with hypertension is not necessarily to increase the bone mass loss.Women are more vulnerable to osteoporosis than men.
出处
《安徽医药》
CAS
2011年第11期1380-1382,共3页
Anhui Medical and Pharmaceutical Journal
关键词
糖尿病
高血压病
T值
diabetes
hypertension
T value
