摘要
目的:探讨纳洛酮联合醒脑静对急性重度酒精中毒的治疗作用。方法:对我院诊治的102例急性重度酒精中毒患者随机分为对照组、纳洛酮组与联合组,对照组采用综合治疗;纳洛酮组,在综合治疗的基础上加用纳洛酮治疗;联合组,在纳洛酮组治疗的基础上加用醒脑静治疗。观察各组的苏醒时间、症状消失时间以及疗效。结果:纳洛酮组的苏醒时间及症状消失时间明显少于对照组且多于联合组,各组结果相比较有统计学意义(P<0.05);纳洛酮组的疗效明显优于对照组,亦同时相比联合组差,各组结果相比较有统计学意义(P<0.05)。结论:纳洛酮联合醒脑静对急性重度酒精中毒患者的疗效高于基础综合治疗以及单用纳洛酮者,值得进一步临床推广。
Objective：To investigate the effect of naloxone combined with Xingnaojing injection on the treatment of acute severe alcoholism. Method：102 patients in our hospital with acute severe alcoholism were divided into the control group,naloxone group and joint group.Using the comprehensive treatment in the control group,using naloxone on the basis of comprehensive treatment in naloxone group.In joint group,using Xingnaojing injection on the basis of treatment of naloxone group.Then observed the awake time,symptoms disappeared time and curative effect of each group. Result：The awake time and symptoms disappeared time of naloxone group was less than the control group,but more than joint group.There were statistically significants between each group（P0.05）.The curative effect of naloxone group was better than the control group but worse than joint group,there were statistically significant between each group（P0.05）. Conclusion：The curative effect of naloxone combined with Xingnaojing injection on the treatment of acute severe alcoholism is better than comprehensive treatment and naloxone therapy alone,it deserves further clinical promotion.
出处
《河北医学》
CAS
2011年第10期1326-1329,共4页
Hebei Medicine
