摘要
目的:探讨尿路感染大肠埃希菌的耐药性变迁,为临床合理用药提供试验依据。方法:对2008～2010年度尿标本检出的234株大肠埃希菌进行超广谱β-内酰胺酶(ESBLs)检测和药敏试验,并对药敏结果进行分析。结果:大肠埃希菌的产酶率呈增高趋势;药敏结果显示大肠埃希菌除对亚胺培南耐药率为0外,对其他常用抗菌药物均出现了不同程度的耐药性,且ESBLs(+)的细菌耐药率普遍高于ESBLs(-)细菌。结论:尿路感染大肠埃希菌耐药现象严重,尤其是ESBLs(+)株,要不断加强耐药性检测,为临床合理用药提供参考。
Objective：To explore the resistance changes of Escherichia coli（E.coli） in urinary tract infection,and provide proofs about the reasonable use of drugs in clinic.Methods：Two hundred and thirty-four strains of E.coli in 2008 to 2010 annual urine specimen with extended-spectrum β-lactamase（ESBLs） detection and drug susceptibility test were detected,and the drug susceptibility results were analyzed.Results：The rate of enzyme production of E.coli showed a rising trend;the drug sensitivity test showed that the resistance existed in normal antibiotics was in different degrees except for Imipenem,and the rate of medical resisitance in ESBLs（＋） bacteria was higher than in ESBLs（-）.Conclusions：The resistance of urinary tract infection which caused by E.coli especially in ESBLs（＋） strains is so serious.It should be strengthen in the detections of the medical resistance,which provide the references for the clinic rational drug use.
出处
《蚌埠医学院学报》
CAS
2011年第10期1113-1115,共3页
Journal of Bengbu Medical College
关键词
尿路感染
大肠埃希菌
药敏试验
超广谱Β-内酰胺酶
urinary tract infection
Escherichia coli
susceptibility test
extended-spectrum β-lactamase
