Translational research and its effects on medicine in China 被引量：5

Translational research and its effects on medicine in China

导出

摘要 Translational research has become a globally recognized model of medical research. Chinese government and doctors have begun to discuss the plan for its development. But most articles are focusing on the advantages rather than its pros and cons. In this essay, the authors discuss the disadvantages of translational research, its effects on clinical work and medical education, highlighting some potential problems and risks in theory and practice on case basis. Some important research management requirements are summarized in this essay to help bring the therapy from the research laboratory to the patient＇s bedside. Translational research has become a globally recognized model of medical research. Chinese government and doctors have begun to discuss the plan for its development. But most articles are focusing on the advantages rather than its pros and cons. In this essay, the authors discuss the disadvantages of translational research, its effects on clinical work and medical education, highlighting some potential problems and risks in theory and practice on case basis. Some important research management requirements are summarized in this essay to help bring the therapy from the research laboratory to the patient＇s bedside.

作者 GUAN Jian CHEN Jie

机构地区 Office of Research Administration Department of Pathology

出处《Chinese Medical Journal》 SCIE CAS CSCD 2011年第19期3170-3175,共6页 中华医学杂志（英文版）

关键词 translational research biological specimen bank medical education intellectual property BIOETHICS translational research biological specimen bank medical education intellectual property bioethics

分类号 Q78 [生物学—分子生物学] D630.1 [政治法律—中外政治制度]

引文网络
相关文献

参考文献30

1Foon KA.Translational research:advancing medical science by stimulating interdisciplinary research.Exp Biol Med 2007;232:713-714.
2Fleming ES,Perkins K,Easa D,Conde JG,Baker RS,Southerland WM,et al.The role of translational research in addressing health disparities:a conceptual frame work.Ethn Dis 2008; 18(2 suppl 2):S2150-S2160.
3Williams R,Mant C,Cason J.The infectious diseases biobank at king's college London:archiving samples from patients infected with HIV to facilitate translational research.Retrovirology 2009; 6:98.
4Barmnes RO,Parisien M,Murphy LC,Watson PH.Influence of evolution in tumor biobanking on the interpretation of translational research.Cancer Epidemiol Biomarkers Prev 2008; 17:3344-3350.
5Roberts J. Personal electronic health records: from biomedical research to people's health.Inform Prim Care 2009; 17:255-260.
6Cambon-Thomsen A,RiaI-Sebbag E,Knoppers BM.Trends in ethical and legal frameworks for the use of human biobanks.Eur Respir J 2007; 30:373-382.
7Sethi P,Theodos K.Translational bioinformatics and healthcare informatics:computational and ethical challenges.Perspect Health Inf Manag 2009; 16:1-13.
8Cheng YF,Jiang J,Hu P,Reinholdsson I,Guo W,Asenblad N.Pharmacokinetics of 8-hour intravenous infusion of NXY-059:A phase Ⅰ,randomized,double-blind (within dose panels),placebo-controlled study in healthy Chinese volunteers.Clin Ther 2008; 30:2342-2353.
9Frantz S.Pharma faces major challenges after a year of failures and heated battles.Nat Rev Drug Discov 2007; 6:5-7.
10Raper SE,Chirmule N,Lee FS,Wivel NA,Bagg A,Gao GP,et al.Fatal systemic inflammatory response syndrome in a ornithine transcarbamylase deficient patient following adenoviral gene transfer.Mol Genet Metab 2003; 80:148-158.