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2型糖尿病患者血清胎球蛋白A水平与胰岛素抵抗的关系 被引量:2

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摘要 目的探讨胎球蛋白A在2型糖尿病胰岛素抵抗中的可能作用及其机制。方法分别收集50例2型糖尿病无大血管病变患者和30例健康对照组为研究对象;采用酶联免疫吸附实验测定各组血清AHSG水平。结果糖尿病组血清AHSG浓度明显高于正常对照组(P<0.01);糖尿病组空腹、餐后2小时胰岛素和胰岛素抵抗指数均较正常对照组升高(P<0.01),胰岛β分泌功能指数则较对照组明显降低(P<0.01);糖尿病组血清AHSG水平与BMI、腰围和臀围呈显著正相关;糖尿病组血清AHSG水平与空腹、餐后2小时胰岛素、C肽和胰岛素抵抗指数均呈显著正相关(P<0.01),与IFI呈显著负相关(P<0.01)。结论血清AHSG可能参与了糖尿病胰岛素抵抗的形成过程。
出处 《中国临床医生杂志》 2011年第11期38-40,共3页 Chinese Journal For Clinicians
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