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血液透析患者极低甲状旁腺激素血症与病死率的关系 被引量：8

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摘要 目的:探讨血液透析患者极低甲状旁腺激素(iPTH)血症与病死率的关系。方法:将2009年3月至2011年3月在四川大学华西医院肾内科血液透析的758例患者按透析前的血清iPTH水平(基线水平)分为两组:1组,血清iPTH≥60pg/mL;2组,血清iPTH<60pg/mL(极低血清iPTH组)。比较两组患者的基本临床特点、生化指标及2年期间的病死率。结果:有12.5%的患者发生极低iPTH血症。与1组相比,2组患者的糖尿病肾病发病率高(P<0.05)、血清白蛋白水平低(P<0.05)和血清钙水平高(P<0.01)。2组患者在第1年和第2年的病死率明显增高(χ2=6.040,P<0.05;χ2=8.269,P<0.005),其血清iPTH与血清钙水平呈负相关(r=-0.498,P<0.05),与血清白蛋白水平呈正相关(r=0.687,P<0.01)。结论:血液透析患者中极低iPTH血症与患者的较高病死率密切相关。在降低iPTH治疗过程中,避免极低iPTH血症,可能有助于改善患者的不良预后。
作者 颜晓勇 黄颂敏 吴蔚桦 薄虹 杨玉玺
机构地区 四川大学华西医院肾内科 遵义医学院附属医院肾内科
出处 《实用医学杂志》 CAS 北大核心 2011年第21期3903-3905,共3页 The Journal of Practical Medicine
关键词 肾透析 甲状旁腺激素 生存率 肾性骨病
分类号 R692.5 [医药卫生—泌尿科学]
  • 相关文献

参考文献17

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同被引文献51

  • 1戎殳,叶朝阳,牛晓萍,高文武,4梅长林.血液透析患者心脏瓣膜钙化及其危险因素[J].中华肾脏病杂志,2004,20(5):364-366. 被引量：39
  • 2卞维静,张凌,谌贻璞,吕滨.血液透析患者冠状动脉电子束CT扫描钙化积分及其相关因素[J].中华肾脏病杂志,2005,21(2):65-68. 被引量：13
  • 3江瑛,王梅.高血磷对慢性肾衰竭大鼠血管钙化的影响[J].中华肾脏病杂志,2007,23(10):663-667. 被引量：7
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实用医学杂志
2011年 第21期

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