摘要
目的:探讨HELLP综合征并发围生儿死亡的危险因素。方法:回顾分析1991年1月至2010年12月天津市中心妇产科医院收治的76例HELLP综合征患者临床资料,按是否发生围生儿死亡分为死亡组和对照组,比较两组患者的一般临床资料和各项实验室指标。结果:围生儿死亡率为22.4%(17/76)。卡方检验结果显示:生产次数、早产情况、胎儿窘迫、收缩压、舒张压、血红蛋白、血小板计数、血清胆红素、24h尿蛋白定量为影响HELLP综合征并发围生儿死亡有统计学意义的因素(P<0.05);Logistic回归分析结果显示:舒张压、血红蛋白、血小板计数、血清胆红素、24h尿蛋白定量是影响HELLP综合征中围生儿死亡有统计学意义的因素。结论:血红蛋白和血小板计数降低及血清胆红素、舒张压和24h蛋白尿升高是影响HELLP综合征围生儿死亡的危险因素。
Objective：To investigate the risk factors of HELLP syndrome complicated with the perinatal mortality.Methods：We reviewed 76 cases with HELLP syndrome from Jan.1991 to Dec.2010,including clinical data.Patients were divided into two groups as the perinatal mortality group and the control group according to the perinatal mortality occurrence or not.General clinical data and various laboratory parameters were comparably gathered and studied between the two groups.Results：The perinatal mortality rate was 22.4%（17/76）.Chi-square test showed labors,premature labor,fetal distress,systolic pressure,diastolic pressure,haemoglobin,platelet count,serum total bilirubin and 24h urine protein were statistically significant factors（P0.05）.Logistic regression analysis showed diastolic pressure,haemoglobin,platelet count,serum total bilirubin and 24h urine protein were statistically significant factors（P0.05）.Conclusion：In this study,the decrease of haemoglobin and platelet count,the increase of diastolic pressure,serum total bilirubin,and 24h urine protein were the risk factors of HELLP syndrome complicated with the perinatal mortality.
出处
《现代妇产科进展》
CSCD
北大核心
2011年第10期777-780,共4页
Progress in Obstetrics and Gynecology
