摘要
目的:考察杭白菊挥发油β-环糊精的制备工艺条件。方法:以包合物的包封率和收得率为考察指标,选择挥发油与β-环糊精的比例、包合温度、超声时间以及超声频率为主要影响因素,进行L9(34)正交试验,优化杭白菊挥发油包合物的工艺条件。结果:优选的包合工艺为挥发油与β-环糊精的用量配比1∶8,包合温度70℃,超声时间15min,超声频率50%。结论:在此条件下杭白菊挥发油包合物的收得率可达83.99%,包合率可达86.69%。此包合工艺稳定可行,优于常规方法。
Objective： To investigate the process research for the preparation of inclusion technology for Volatile Oil in Chrysanthemum morifolium Ramat.Method： The experiments were designed with orthogonal experiment,using the yield and inclusion rate of volatile oil which were used as indexes to optimize the process.Results： The optimum inclusion condition was that volatile oil∶β-CD in proportion as 1∶ 8 was mixed,and the ultrasonic reaction time is 15 minutes,70℃ in 29Hz.Conclusion： This inclusion technology is simple,stable and superior to the used.
出处
《中华中医药学刊》
CAS
2011年第11期2504-2505,I0002,共3页
Chinese Archives of Traditional Chinese Medicine
基金
浙江省医药卫生科学研究基金计划资助项目(2010KYA006)
关键词
杭白菊挥发油
Β-环糊精
超声包合
正交试验
Volatile Oil in Chrysanthemum morifolium Ramat
β-cyclodextrin
ultrasonic inclusion
orthogonal experiment
