期刊文献+

钙拮抗剂诱导牙龈增生的临床研究 被引量:9

Clinical study of gingival overgrowth induced by calcium channel blockers
原文传递
导出
摘要 目的探讨钙拮抗剂诱导的牙龈增生与钙拮抗剂种类和牙周局部因素的关系。方法2007年3月至10月对河北省人民医院心血管内科和口腔科门诊240例服用钙拮抗剂类药物患者进行牙周检查,记录牙龈增生指数、出血指数和菌斑指数等。结果240例患者中64例(26.67%)发生了牙龈增生,服用不同类型钙拮抗剂的患者间牙龈增生的发生率差异无统计学意义(P均>0.05)。牙龈增生程度越重,菌斑指数和出血指数均值越高,与0度组相比,Ⅰ~Ⅳ度牙龈增生组的菌斑指数和出血指数差异均有统计学意义(P均<0.01)。结论钙拮抗剂诱导的牙龈增生程度与牙周局部因素密切相关,与钙拮抗剂种类无关。 Objective To study relationship of gingival overgrowth induced by calcium channel blockers with types of calcium channel blockers and periodontal local factors.Methods Relationship of types of calcium channel blockers and gingival overgrowth,degree of gingival overgrowth and plaque index and probing bleeding index were studied in 240 parients who were taking calcium channel blockers.Results Gingival overgrowth occurred in 64 patients(26.67%),there were no significant difference between types of calcium channel blockers and gingival overgrowth;there were significant difference between degree of gingival overgrowth and plaque index and probing bleeding index.Conclusion Gingival overgrowth induced by calcium channel blockers has close relationship with periodontal local factors,and no relationship with types of calcium channel blockers.
出处 《中国实用口腔科杂志》 CAS 2008年第3期161-162,共2页 Chinese Journal of Practical Stomatology
关键词 钙拮抗剂 牙龈增生 菌斑指数 出血指数 calcium channel blockers gingival overgrowth plaque index bleeding index
  • 相关文献

参考文献7

  • 1Inglés E,,Rossmann JA,Caffesse RG.Newclinical index for drug-induced gingival overgrowth. Quintessence International . 1999
  • 2Fujii A,Matsumoto H,Nakao S,et al.Effect of calcium-channel blockers on cell proliferation,DNA synthesis and collagen synthe-sis of cultured gingival fibroblasts derived from human nifedipine responders and non-responders. Archives of Oral Biology . 1994
  • 3Ellis JS,Seymour RA,Steele JG,et al.Prevalence of gingival over-growth induced by calcium channel blockers:a community-based study. Journal of Periodontology . 1999
  • 4Jaume Miranda, Llu&iacute,s Brunet, Pere Roset, Leonardo Berini, Mag&iacute,Farr&eacute,and Carlos Mendieta&lt;.Prevalence and risk of gingival overgrowth in patients treated with diltiazem or verapamil. Journal of Clinical Periodontology . 2005
  • 5Heijl L,Sundin Y.Nifedipine - induced gingival overgrowth in dogs. Journal of Periodontology . 1989
  • 6Miranda J,Brunet L,Roset P,et al.Prevalence and risk of gingival enlargement in patients treated with nifedipine. Journal of Periodontology . 2001
  • 7Peter Meisel, Christian Schwahn, Ulrich John, Heyo K. Kroemer &amp,Thomas Kocher&lt;.Calcium antagonists and deep gingival pockets in the population-based SHIP study. British Journal of Clinical Pharmacology . 2005

同被引文献108

引证文献9

二级引证文献33

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部