摘要
以８４例晚期卵巢癌患者采用顺铂或卡铂为主的联合化疗方案行全身化疗或腹腔化疗。卡铂用药组总有效率为５５．６％，一年生存率为７７．３％；顺铂用药组总有效率为５６．４％，一年生存率为９０％。卡铂组胃肠反应较顺铂组轻，血液毒性较顺铂重。未研究结果表明：卡铂尚不能常规替代顺铂治疗卵巢癌，顺铂腹腔化疗可作为晚期卵巢癌和复发卵巢癌的首选治疗。
4 patients with advanced ovarian
cancer had been treated in our hospital,45 patients were treated by
CP─con-taining regimens,24 patients were administered by the
intraperitoneal route(IP)with CF(CP + 5─Fu),21 by in-traverous
infusion (IV)with CVC(CP+VCR+CTX),39 patient were treated by DDP─
containing regimens,22 byIP with PF(DDP+5─Fu),13 by IV with
PVC(DDP+VCR+CTX),The response rate was 55. 6%for CP contain-ing
regimens and 56.4%for DDP containing regimens.Gastrointestinal
reaction and renal toxicity were less severe inCP containing regimens
than DDP containing regimens.However CP had more marked
myelosuppessive effect.
出处
《中华肿瘤防治杂志》
CAS
1995年第3期197-199,共3页
Chinese Journal of Cancer Prevention and Treatment
关键词
卡铂
顺铂
卵巢恶性肿瘤
Carboplatin(CP):cisplatin(DDP):Advan
cancer
