摘要
目的:研究疮疡灵/明胶海绵复合物体外释放率,探讨其质量控制的方法。方法:采用气相色谱法对疮疡灵/明胶海绵复合物主要成分进行体外释放度的测定。结果:溶液24 h内基本稳定,冰片1、2、24 h的累积释放率分别为36.79%、54.54%、96.12%,释放时间达24 h。结论:该制剂方法设计合理,稳定性良好,制备方法可行,所建立的质量标准可用于疮疡灵/明胶海绵复合物的质量控制。
Objective： To study on the release of Chuangyangling/Absorbable Gelatin Sponge Compound and establish its quality standard.Methods： Gas chromatography was used to examine the release rate in vitro of the main ingredients of Chuangyangling/Absorbable Gelatin Sponge Compound.Results： The solution was stable within 24 h basically.The release rate of Borneol at 1,2,24 h was 36.79%,54.54%,96.12% respectively.Conclusion： The method of design is reasonable with well stability.The established quality standard is applicable for the quality control of Chuangyangling/Absorbable Gelatin Sponge Compound.
出处
《中国医药导报》
CAS
2011年第33期40-42,共3页
China Medical Herald
关键词
疮疡灵/明胶海绵复合物
体外释放率
气相色谱法
Chuangyangling/Absorbable Gelatin Sponge Compound
Release rate in vitro
Gas chromatography
