摘要
目的探讨帕瑞昔布钠用于上肢骨折手术对芬太尼术后镇痛效果的影响。方法将90例患者分为对照组和实验组,在手术结束前15min,对照组患者给予静脉注射2mL生理盐水,实验组患者给予静脉注射40mg帕瑞昔布钠。结果术后5、7、11h组间VAS评分比较差异有统计学意义(P<0.05);术后2、24h两组间的VAS评分比较,差异无统计学意义(P>0.05);与对照组相比,实验组患者镇痛泵按压次数以及镇痛泵外芬太尼静脉追加次数明显低于对照组,差异有统计学意义(P<0.05);实验组患者嗜睡、恶心等不良症状的发生率较低(P<0.05)。结论帕瑞昔布钠能够有效减少上肢骨折手术芬太尼静脉镇痛的不良反应以及有效提高术后镇痛效果,具有安全性和有效性。
Objective To explore the influence of parecoxib sodium on the postoperative analgesic effect of fentanyl for upper limb fracture surgery. Methods Ninty cases were were divided into control and experimental groups, 15min before the end of surgery, the control group was treated with intravenous saline 2mL and the experimental group was treated with intravenous parecoxib sodium 40rag. Results Postoperative 5,7,11 hours,VAS scores between groups had statistically significant difference（P〈0.05）;Postoperative 2,24 hours, VAS scores between the two groups had no statistically significant difference（P〉0.05）;Comparing with the control group,the press numbers of analgesic pump and additional number of intravenous fentanyl outside the analgesic pump of experimental group were significantly lower than those of the control group, and the differences were statistically significant （P〈0.05）;The incidences of drowsiness, nausea and other adverse symptoms of experimental group were lower （P〈0.05）. Conclusion Parecoxib sodium can effectively reduce the adverse effects of fentanyl for upper limb fracture surgery and effectively improve the analgesic effect, with the safety and effectiveness.
出处
《中国现代医生》
2011年第34期98-99,共2页
China Modern Doctor
关键词
帕瑞昔布钠
上肢骨折手术
芬太尼
镇痛效果
Parecoxib sodium
Upper limb fracture surgery
Fentanyl
Analgesic effect
