摘要
目的通过建立一种新的手术模型,实现对脑脊液(CSF)的多次采集。方法研究Beagle犬头颅结构,定位手术钻孔,手术穿刺、埋管采集脑脊液。结果动物手术存活率为80%,模型成功率为60%。结论新模型设计合理,有利于多次采集,此方法可成为Beagle犬脑脊液采集新手段。
Objective To establish a novel surgical model of multi-collecting cerebrospinal fluid（CSF） in Beagle dog and assess the surgical effect.Methods With investigating the construction of skull of beagle dog,deciding the position of surgical point,completed the collecting process by skull puncture,collection tube covering and cerebrospinal fluid multi-drawing.Results We successfully explore a novel surgery of collecting cerebrospinal fluid,with the successful rate up to 70%.Conclusions The new model to cerebrospinal collect is favor of multi-draw CSF.It is a potential model to be popular method in colleting CSF.
出处
《实验动物科学》
2011年第5期69-71,共3页
Laboratory Animal Science
基金
浙江省医学科学院青年基金项目(A类)(No.AA0914E)
国家自然科学基金项目(No.30701064)
关键词
手术模型
脑脊液
定位
多次采集
surgical model
cerebrospinal fluid
surgical position
multi-collection
