摘要
目的探讨非酒精性脂肪性肝病与尿酸的关系。方法在本院体检的人群中随机抽取非酒精性脂肪性肝病(NAFLD)患者200例为观察组,体检健康人群200例为对照组。检测尿酸、血脂等相关指标,并进行统计学分析。将NAFLD组分为非高尿酸血症组和高尿酸血症组,统计分析两组的生化指标。结果 NAFLD组较对照组尿酸水平有显著增加,高尿酸血症患者比例显著提高。200例非酒精性脂肪性肝病患者按年龄及性别分层后,男性组35～50岁高尿酸血症患病率达峰值,为49.15%;女性组50～65岁患病率达峰值,为42.11%;不同年龄段男女性别不同,患病率不同。NAFLD患者非高尿酸血症组与高尿酸血症组甘油三酯、总胆固醇、低密度脂蛋白比较差异有统计学意义(P<0.05)。结论 NAFLD与高尿酸血症有一定关系。
Objective To explore the relationship between uric acid and nonalcoholic fatty liver disease. Methods In the population of physical examination in our hospital, taking a random sample of non - alcoholic fattyliver disease （NAFLD） 200 patients as the observation group, of healthy people as the control group. The parameters of their uric acid, blood fat and so on were investigated and statistical analyzed. The observation group also divided into non - hyperuricemia and hyperuricemia groups and the biochemical parameters were statistical analysed. Results NAFLD group than the control group a significant increase in uric acid levels, high uric acid significantly increased the proportion of patients. 200 cases of non - alcoholic fatty liver disease patientsstratified by age and sex, the male age group 35 to 50 prev- alence rate of hyperuricemia peak of 49. 15% ; female group of 50 to 65 years the peak prevalence rate for 42. 11% ; different age groups of different gender, different prevalence. Hyperuricemia in patients with NAFLD group and the non - hyperuricemia triglyceride, total cholesterol, LDL difference was statistically significant （ P 〈 0.05 ）. Conclusion Nonalcoholic fatty liver disease correlated positively to hyperuricemia.
出处
《中国医学创新》
CAS
2012年第1期3-5,共3页
Medical Innovation of China
关键词
非酒精性脂肪性肝病
尿酸
危险因素
Nonalcoholic fatty liver disease
Uricacid
Risky factor
