摘要
目的探讨尼莫地平注射液对预防和治疗卒中相关性头痛的使用方法和临床疗效。方法设立试验组及对照组,实验组给予尼莫地平注射液4mg输液泵缓慢泵入,每日1次,1周为一疗程,可多疗程治疗;对照组给予氟桂利嗪胶囊及麦角胺类制剂治疗。结果治疗组控制73.5%,显效17.1%,无效9.4%,总有效率为90.6%;对照组控制37.5%,显效12.5%,无效50%,总有效率为50%。两组相比临床疗效有显著差异(P<0.05)。结论尼莫地平为钙离子拮抗剂,有抗缺血、缺氧、抗惊厥,保护神经元的结构和功能的作用,同时不引起缺血现象。通过观察,其治疗卒中相关性头痛,效果好,不良反应较轻微,而且副作用小、安全、价廉、无依赖性,值得推广。
Objective Explore nimodipine injection on the prevention and treatment of stroke use method and correlation headache clinical curative effect.Methods The establishment of experimental group and control group,Experimental group give nimodipine 4 mg infusion pump injection pump into the slow,1 times a day,1 week for a course of treatment,but many courses of treatment;The control group was given flunarizine capsules and ergot amine formulations in the treatment of.Results Treatment group,control 73.5%,effective in 17.1%,9.4% invalid,the total effective rate was 90.6%;the control group,control 37.5%,effective in 12.5%,50% invalid,the total effective rate was 50%.Two groups have significant difference compared to clinical curative effect（P0.05）.Conclusion Nimodipine for calcium channel blockers,have against ischemic,hypoxia,resistance to convulsions,protection of neurons to the structure and function of role,and not cause ischemic phenomenon.Through the observation,the correlation between the treatment of stroke headache,the effect is good,bad reaction with minor,and side effects of small,cheap,safe and no dependence,is worthy to be popularized.
出处
《当代医学》
2012年第3期140-141,共2页
Contemporary Medicine
关键词
尼莫地平注射液
治疗
卒中相关性头痛
疗效观察
Nimodipine Injection
Treatment
stoke associated headache
Observation of curative effect
