摘要
目的分析246例乳腺癌临床病理特性对判断预后的价值。方法选取徐州医学院附属医院1999～2001年有确切随访资料的246例乳腺癌患者,采用Kaplan-meier法与Cox回归模型评估各因素对乳腺癌预后的影响。结果本组246例乳腺癌病例5年总体生存率为79.02%,使用SPASS软件进行Pro Logistic回归分析患者5年总体生存率与绝经状况、肿瘤大小复发情况、腋窝淋巴结转移、TNM分期、化疗、内分泌治疗、放疗均显著相关而与PR、ER、病理类型和年龄无明显关系。单因素分析淋巴结状态和复发情况是乳腺癌患者独立危险因素,且多因素分析淋巴结状态和复发情况是女性乳腺癌患者最明显的预后协同危险因素。结论患者绝经状况、肿瘤大小、复发情况、腋窝淋巴结转移、TNM分期、化疗、内分泌治疗、放疗的不同水平5年生存率有显著差异。淋巴结转移和复发情况不仅是影响乳腺癌患者预后的独立危险因素,同时更是影响乳腺癌预后的联合危险因素。
Objective To Analyze clinical pathology characteristic in 246 breast carcinomas and evaluate the value.Methods 246 cases with breast carcinomas were selected in affiliated hospital of Xuzhou between 1999 and 2001,adopted Kaplan-meier method and Cox return to evaluate influence of each factor to the mammary glands cancer.Results The survival rate of 246 cases with breast carcinomas for total 5 years is 79.02%,usage the SPASS 11.0 software carry on Pro Logistic back to return analysis sufferer total for 5 years survival rate with menopause,relapse,tumor size,lymphoid knot transfer,TNM stage,chemotherapy,endocrine treatment,radiotherapy to all show significant correlated but with PR,ER,pathology type and age had no obvious relation.List factor analysis lymphoid knot transfer and relapse were independence dangerous factors of breast carcinoma,and many factor analysis lymphoid knot transfer and relapse were in conjunction with dangerous factor of breast carcinoma.Conclusions Menopause,tumor size,relapse,lymphoid knot transfer,TNM stage,chemotherapy,endocrine treatment,radiotherapy of dissimilarity level which have already shown significant deviation of 5 years survival rate.Lymphoid knot transfer and relapse is not only independent dangerous factor to breast carcinomas prognosis,but also relevant factors.
出处
《齐齐哈尔医学院学报》
2011年第24期3958-3960,共3页
Journal of Qiqihar Medical University
关键词
乳腺癌
生存率
预后
Breast carcinomas Survival rate Prognosis
